Other Bacteria

Question 1

Undulating fever due to contaminated dairy

Answer 1

Brucellosis

Tx doxycycline + rifampicin

Question 2

Tularemia

Answer 2

Francisella Tularensis

Tx Streptomycin or gentamicin

Question 3

Gram (-) rods w/ bipolar (safety pin) staining causing bubonic, pneumonic and septicemic plague

Answer 3

Yersinia pestis

Tx. Streptomycin and tetracycline

Question 4

Most virulent bacteria

Answer 4

Yersinia pestis

Question 5

Gram (-) encapsultated rod forming buttery colonies with musty odor
Animal bites and osteomyelitis

Answer 5

Pasteurella multocida

Tx. Pen G

Question 6

Aerobic, acid fast rods grown in Ziehl-Neelsen

Answer 6

Mycobacterium tuberculosis

Question 7

Assay used for mycobacterium drug resistance

Answer 7

Luciferase assay

Question 8

Most important virulence factor in Mycobacterium

Answer 8

Cord factor

Question 9

Virulence factor in Mycobacterium that prevents phagosome-lysosomal fusion

Answer 9

Exported repetitive protein (sulfatides->surface glycolipids

Question 10

Virulence factor in Mycobacterium that elicits delayed hypersensitivity

Answer 10

Tuberculin surface proteins

Question 11

Primary complex in PTB

Answer 11

Ghon’s complex

Radiologically detectable colonization (Ranke’s complex)

Question 12

Reactivation Tuberculosis

Answer 12

Simon’s Focus
CXR: Cicatricial changes, subpleural blebs, cavitations
Secondary colinzation w/ A. fumigatus

Question 13

Positive Mantoux test for Low risk population

Answer 13

> 15 mm

Question 14

Positive Mantoux test for HIV+, AIDS, old TB Immunocompromise population

Answer 14

> 5 mm

Question 15

Positive Mantoux test for High risk population

Answer 15

> 10 mm

Question 16

Most common extrapulmonary for of TB

Answer 16

Scrofula (TB Lymphadenitis)

Question 17

Other uses of BCG vaccine aside from TB prevention

Answer 17

Adjunct treatment for bladder CA

Question 18

Causes pulmonary disease in immunocompromised host (AIDS patient with CD4<50)

Answer 18

Mycobacterium Avium-intracellulare complex (MAI, MAC)

Prophylaxis: Azithromycin

Question 19

Aerobic, acid fast rods w/c can’t be cultured in vitro and causes neural disease w/ dermatologic manifestation

Answer 19

Mycobacterium leprae

Question 20

Leprosy with hypopigmented plaques, thickened superficial nerves, and significant anesthesia

Answer 20

Tuberculoid Leprosy

Tx. Dapsone and rifampin

Question 21

Leprosy with leonine facies, erythema nodosum leprosum

Answer 21

Lepromatous leprosy

Tx. dapsone, rifampin and clofazimine

Question 22

DOC for erythema nodosum leprosum

Answer 22

Thalidomide

Question 23

Condition associated with a hard nontender swelling with sinus tracts draining sulfur granules in a setting of broken jaw or dental extraction

Answer 23

Actinomycosis (lumpy jaw)

Tx. Pen G + drainage

Question 24

African with unilateral swelling of the jaw. Think of ?

Answer 24

Burkitt’s, Lymphoma, EBV

Question 25

Gram (+) aerobic acid fast (Fite-Faraco- stain) which causes mycetomas and lung and brain abscesses (orange colonies)

Answer 25

Nocardia asteroides, Nocardiosis | Tx. TMP-SMX

Question 26

Smallest free living organism

Answer 26

Mycoplasma Pneumoniae

Question 27

Manifest as broad based ataxia, (+) romberg, charcot joints, stroke w/o hypertension

Answer 27

Tertiary Syphilis

Question 28

Tertiary syphilis

Answer 28

``` Gummas Neurosyphilis - tabes dorsalis - dementia paralytica Aortitis --> endarteritis ```

Question 29

Manifest with snuffles/saddle nose; mulberry molars; hutchinson triad, saber shins, higoumenakis sign, clutton's joints, pulmonary hemorrhage

Answer 29

Congenital syphilis

Question 30

Hutchinson triad

Answer 30

Hutchinson teeth, deafness, keratitis

Question 31

Detection for Primary syphilis

Answer 31

Dark field microscopy

Question 32

Detection for Secondary & Tertiary syphilis

Answer 32

RPR/VDRL

Question 33

Largest medically important bacteria

Answer 33

Borrelia burgdorferi

Question 34

Lyme disease is transmitted through

Answer 34

deer ticks (Ixodes scapularis)

Question 35

Pathognomonic sign: Erythema chronicum migrans

Answer 35

Lyme Disease

Question 36

Stage of lyme disease with autoimmune migratory polyarthritis (onion skin lesions),acrodermatitis chronica atrophicans

Answer 36

Stage 3

Question 37

Stage of lyme disease with myocarditis (AV block), meningitis and bells palsy

Answer 37

Stage 2

Question 38

Lyme Disease

Answer 38

``` BAKE a Key Lyme pie Bell's palsy Arthritis Kardiac block Erythema chronicum migrans ```

Question 39

DOC for lyme disease

Answer 39

Early: Doxycycline Late: IV penicillin or ceftriaxone

Question 40

Relapsing fever

Answer 40

Borrelia recurrentis | Tx Tetracycline

Question 41

Shepherd's crook

Answer 41

Leptospira interrogans

Question 42

Obligate intracellular bacteria Cell wall lacks muramic acid Grown in cycloheximide culture

Answer 42

Chlamydia Trachomatis

Question 43

Obligate intracellular bacteria

Answer 43

Chlamydia Trachomatis | Ricketssia

Question 44

Chronic keratoconjunctivitis progressing to scarring and blindness

Answer 44

Trachoma | Chlamydia trachomatis

Question 45

Etiologic type of trachomatis that cause trachoma

Answer 45

C. trachomatis types A-C

Question 46

Etiologic type of trachomatis that cause genital tract infection

Answer 46

C. trachomatis types D-K

Question 47

Etiologic type of trachomatis that cause neonatal pneumonia

Answer 47

C. trachomatis types D-K

Question 48

Etiologic type of trachomatis that cause lymphogranuloma venereum

Answer 48

C. trachomatis types L1-L3

Question 49

Papule or vesicular w/c ulcerates and leads to suppurative inguinal lymphadenitis (buboes) (+) Frei test

Answer 49

Lymphogranuloma venereum

Question 50

``` DOC of Chlamydia infections STD Conjunctivitis LGV Psittacosis ```

Answer 50

STD Azithromycin Conjunctivitis Erythromycin LGV Doxycycline Psittacosis Azithromycin

Question 51

Condition where there is sudden onset pneumonia w/ malaise, fever, anorexia, sore throat, photophobia, severe headache (+) bird exposure (bird fancier's disease)

Answer 51

Psittacossis

Question 52

(+) Weil-Felix reaction

Answer 52

Rickettsiae

Question 53

Cat scratch fever in immunocompetent individuals | Bacillary angiomatosis in immunocompromise individuals

Answer 53

Bartonella henselae

Question 54

Reservoir dogs | forms morulae in cytoplasms of monocytes

Answer 54

Ehrlichia chaffeensis

Question 55

Messenteric Adenitis (pseudoappendicitis)

Answer 55

Yersinia enterocolitica

Question 56

Granuloma Inguinale (Donovanosis)

Answer 56

Klebsiella granulomatis

Question 57

small painless papule ulcerates to form beefy red ulcers with velvety surface pseudobuboe formation

Answer 57

Granuloma Inguinale (Donovanosis)