Drug Cards quiz 2

Question 1

Hormone

Answer 1

Testerone Gel
Progesterone oral
Estrogens conjugated

Question 2

Testosterone Gel
Progesterone oral
Estrogens conjugated

Answer 2

Androgel, Fortesta, Testim
Prometrium
Premarin

Question 3

Hormone Indication

Answer 3

Testosterone :
deficiency/absence of testosterone
Progesterone:
-Prevention of endometrial hyperplasia in postmenopausal
-Secondary Amenorrhea
Estrogens:
–Vasomotor symtoms w/ menopause
-Female hypogonadism
-Female castration and primary ovarian failure
-Breast cancer
-Prostatic cancer
-Prostastic carcinoma
-Post menopausal osteoporosis

Question 4

Hormone Doses

Answer 4

Testosterone Gel: 50 mg
Progesterone : 200 mg
Estrogen: 1.25 mg

Question 5

Hormone MOA

Answer 5

-Testosterone:
Inhibit/stimulate mRNA transcription
-Progesterone: Increased synthesis of RNA
-Estrogen:stimulate specific RNA and protein synthesis @female sex organs
decrease FSH,LH,

Question 6

Hormone
Interactions

Answer 6

Testosterone : insulin,corticosteroids
Progesterone : ketonazole
Estrogen : rifampin,hydratoins

Question 7

Hormone
Contradiction

Answer 7

Testosterone :cancer, women, children, heart failure
Progesterone: cancer,peanut allergy, pregnancy, thrombophlebitis, liver dysfunction
Estrogen: breast cancer, neoplasia, pregnancy, genital bleeding ,nursing mothers

Question 8

Hormone
Adverse effects

Answer 8

Testosterone :Increased PSA, emotional ,hypertension,Increased hemoglobin
Progesterone: abdominal pain, viral infection, cough,breast pain
Estrogen: alopecia ,hirsutism, abnormal menstrual bleeding, weight changes

Question 9

Hormone
PC

Answer 9

Testosterone: No genital area,
Avoid showering
Monitor: hematocrit,hemoglobin,testosterone,psa,lipid panel,lft
Progesterone: caution when performing activities
Estrogen : discontinue if pregnant

Question 10

Antibacterial
(TetracyclineAntibiotic)
(Macrolide Antibiotic)

Answer 10

Minocycline Hydrochloride

Doxycycline Hyclate

Azithromycin Dihydrate

Question 11

Minocycline Hydrochloride
Azithromycin Dihydrate
Doxycycline Hyclate

Answer 11

Minocin, Dynacin,Solodyn ER
Zithromax, Zmax
Vibramycin, Doryx

Question 12

Antibacterial
Indications
TetracyclineAntibiotic)
(Macrolide Antibiotic)

Answer 12

Syphilis, Gonorrhea, chlamydia/ureaplasma
Minocin : meningitidis
Doryx : Malaria
Exception
Zmax: otitis media, pneumonia, ,ulcer

Question 13

Antibacterial
TetracyclineAntibiotic)
(Macrolide Antibiotic)
MOA

Answer 13

competitively binding to 30S ribosomal subunits in bacteria

Question 14

Antibacterial
Interactions
TetracyclineAntibiotic)
(Macrolide Antibiotic)

Answer 14

Doryx, Minocin : bactericidal antibiotics, oral contraceptives AL,Ca,Mg,Zn,Fe
Minocin, Zmax: antacids

Question 15

Antibacterial
contraindications
TetracyclineAntibiotic)
(Macrolide Antibiotic)

Answer 15

-impaired renal fxn
Minocin, Doryx : children under 8, pregnancy and lactation
Zmax: low K, Mg or bradycardia, arrhythmia

Question 16

Antibacterial
TetracyclineAntibiotic)
(Macrolide Antibiotic)
adverse effects

Answer 16

Dizziness,Nausea, Diarrhea, abdominal pain
Minocin, Doryx: Vertigo, teeth discoloration
Doryx: sunlight sensitivity

Question 17

Antibacterial
PC
TetracyclineAntibiotic)
(Macrolide Antibiotic)

Answer 17

-empty stomach with full glass of water (Zmax formulations)
Minocin and Zmax: No antacids
Doryx: Monitor CBC

Question 18

Osteoporosis Agent

Answer 18

Alendrote Sodium
Raloxifene Hydrochloride

Question 19

Alendrote Sodium
Raloxifene Hydrochloride

Answer 19

Fosamax
Evista

Question 20

Osteoporosis Agent
Indications

Answer 20

Osteoporosis in post menopausal women
Evista : 60 mg (only women)
Fosamax : 10 mg
Fosamax : Bone problems in men

Question 21

Osteoporosis Agent
MOA

Answer 21

Evista : selective estrogen receptor modulator
Fosamax : inhibits osteoclast activity

Question 22

Osteoporosis Agent
Interactions
CAA

Answer 22

Fosamax : Ca, antacids,aspirin
Evista : NSAIDs, cholestyramine

Question 23

Osteoporosis Agent
Contraindication

Answer 23

Nursing mothers
Evista : Pregnancy
Fosamax : GI problems

Question 24

Osteoporosis Agent
Adverse effects

Answer 24

Fosamax : flatulence,osteonecrosis, musculoskelteal pain
Evista : hot flashes,sinustis,edema

Question 25

Osteoporosis Agent PC

Answer 25

swallow whole Fosamax : dont lie down right after for 30 Monitor BMD Evista : avoid not moving, take Ca and Vit D

Question 26

NSAIDs

Answer 26

Celecoxib Ibuprofen Naproxen Meloxicam Nabumetone Diclofenac NA oral Diclofenac NA topical

Question 27

Celecoxib Ibuprofen Naproxen Meloxicam Nabumetone Diclofenac NA oral Diclofenac NA topical

Answer 27

Celebrex Motrin Naprosyn Mobic,Vivlodex,Anjeso Relafen Volteren & XR Volteren gel

Question 28

NSAIDs indication

Answer 28

Arthritis Celecoxib : 200mg (100,200,400) Ibuprofen : 1200-3200( 400,600,100) Naproxen : 250 to 500(250,375,500) Meloxicam : 7.5(7.5,15) Nabumetone : 500 to 2000( 550,750) Diclofenac NA oral : 50,75,XR 100 Diclofenac NA topical: 2g up, 4g low Painful periods Celecoxib : 400 Ibuprofen : 500 Naproxen : 500

Question 29

NSAIDs MOA

Answer 29

COX inhibitor

Question 30

NSAIDs interactions

Answer 30

Aspirin, Exception (Topical,Nabumetone) : Lithium

Question 31

NSAIDs Contraindication

Answer 31

Bleeding,thrombotic events

Question 32

NSAIDS adverse effects

Answer 32

Gastrointestinal problems Exception (Celecoxib,oral ,meloxicam) : rash,pruritus Celecoxib : sinutis, edema

Question 33

NSAIDs PC

Answer 33

Naproxen : empty stomach, no children Nabumetone, Oral: alcohol oral : swallow whole topical : don't shower after application 1 hour , nothing on it, sunlight exposure Monitor LFT and RFT Naproxen : RFT no monitor for topical