Drug Delivery Routes

Question 1

Systemic

Answer 1

Enteral and Parenteral

Question 2

Local

Answer 2

Topical

Question 3

Drug to Body
Refers to the GI Tract
(oral, duodenal, gastric, rectal)

Answer 3

Enteral

Question 4

Oblong Shape

Answer 4

Enteral

Capsule

Question 5

Round shape

Answer 5

Enteral

Tablet

Question 6

Cross shaped

Answer 6

Enteral

Caplet

Question 7

Prevents dissolving quickly

Answer 7

Enteral

Enteric Coated

Question 8

Advantages of Enteral

Answer 8

Safe 
Convenient 
Self Administered 
Economical 
Non Invasive

Question 9

Disadvantage of Enteral

Answer 9

Slow Action
GI Irritation
Cannot be given to unconscious patients
May undergo First Pass Metabolism

Question 10

Going to the tissues

Outside the GI Tract

Answer 10

Parenteral

Question 11

Injecting through SKIN

Answer 11

Parenteral

Intradermal

Question 12

Injecting UNDER the SKIN

ex. insulin

Answer 12

Parenteral

Subcutaneous

Question 13

Injecting directly ON THE MUSCLE
(IM)
Large skeletal

Answer 13

Parenteral
Intramuscular
IM

Question 14

Injecting into a VEIN

Answer 14

Parenteral
Intravenous
(IV)

Question 15

Gaseous substance is introduced to the body via Pulmonary Epithelium - Respiratory System

Answer 15

Parenteral

Inhalation

Question 16

Used to release a drug slowly by absorption on the skin

Ex Patches

Answer 16

Parenteral

Transdermal

Question 17

Giving a drug across mucous membranes in the mouth

Answer 17

Parenteral

Transmucosal

Question 18

Behind the Eye

Paralyze it

Answer 18

Retrobulbar

Question 19

Injecting into the Episclera

Answer 19

Subconjunctival

Question 20

Injecting into the Anterior Chamber

Answer 20

Intracameral

Question 21

Injecting into the Vitreous

Answer 21

Intravitreal

Question 22

Advantages of Parenteral

Answer 22

Rapid 
More predictable 
Avoids first pass metabolism 
Avoids GI irritation 
Easy for unconscious patients

Question 23

Disadvantages of Parenteral

Answer 23

May be painful 
Could damage the nerves 
More expensive 
Less safe 
Keep everything sterile

Question 24

Application of drug to the skin or mucous membranes

Answer 24

Local

Topical

Question 25

Topical Medical Administration

Answer 25

``` Ointment Cream Gel Powder Paste Mucous Membrane ```

Question 26

Advantages of Local

Answer 26

``` Low risk of systemic adverse effects Low risk of drug interactions Small amount of drug is used Ease of administration to uncooperative / unconscious patients Low cost Avoids first pass metabolism ```

Question 27

Disadvantages of Local

Answer 27

Potential allergic contact dermatitis Reduced penetration to target area Thickness of skin impacts absorption speed Time consuming to apply

Question 28

Innovative Drug Delivery Advantages

Answer 28

``` Improves compliance Drug stays in the tissue even after lens removal Continuous drug delivery Avoids need for drops or surgery Not very invasive ```

Question 29

Suppositories

Answer 29

Absorbed through the butt

Question 30

? Feeding tubes in the intestine

Answer 30

Gastrostomy Tube

Question 31

Sublingual

Answer 31

Under Your Tongue