Pharmacology Terminology

Question 1

What is Pharmacology?

Answer 1

Science that deals with the study of drugs and their interaction with living systems

Question 2

Derived from Greek words
“Pharamcon” meaning,,?
“Logos” meaning..?

Answer 2

Biologically active substance

Study

Question 3

Derived from a French word

“Drogue”

Answer 3

Drug

Question 4

Examples of Drugs

Answer 4

Natural or Synthetic

Question 5

Tylenol

Answer 5

Trade Name

Question 6

Acetaminophen

Answer 6

Generic Drug Name

Question 7

N-(4- Hydroxyphenyl) Acetamide

Answer 7

Chemical Drug Name

Question 8

PharmacoKINETICS

Answer 8

Study of what the BODY does to a DRUG 
Body -> Drug
Absorption 
Distribution 
Metabolism
Excretion

Question 9

ABSORPTION
DISTRIBUTION
METABOLISM
EXCRETION

Answer 9

PharmacoKINETICS

Question 10

PharmacoDYNAMICS

Answer 10

Study of EFFECTS of the DRUG on the BODY

Drug -> Body

Question 11

Effects of Pharmaceuticals

Answer 11

Therapeutic Effect

Adverse Effect

Question 12

The INTENDED EFFECT of the drug on the body

Answer 12

Therapeutic Effect

Question 13

Effects of the drug on the body that are nuisance and cause slight discomfort

Answer 13

Side Effect

Question 14

Ingredient in a drug that is biologically active

Answer 14

Active Ingredient

Question 15

Inactive compound metabolized in the body to create the drug

Answer 15

Prodrug

Question 16

Amount of time a product is left to use

Answer 16

Shelf Life

Question 17

Estimated date based on drug stability test

Answer 17

Expiration

Question 18

Specific instructions how to use the drug

Answer 18

Labelled Indication

Question 19

Use of pharmaceutical drugs for an unapproved indication

Answer 19

Off Label Prescribing

Question 20

Substance

Answer 20

Ligand

Question 21

Where does a Ligand bind to create a drug - receptor complex?

Answer 21

Receptor

Question 22

Type of drug that binds to cells to produce an ENHANCE physiological response?
“switched on” effect?

Answer 22

Agonist

Question 23

Type of drug that BLOCKS access to a receptor and results in a REDUCED cellular activity?

Answer 23

Antagonist

Question 24

Effect that is undesired and a harmful effect resulting from a medication or other intervention
Unwanted, uncomfortable and dangerous effect

Answer 24

Adverse Effect

Question 25

Entrance or movement of a drug into the blood stream | Must be dissolve in body fluids except IV

Answer 25

Absorption

Question 26

Disbursement of unmetabolized drugs as it moves through the body's blood and tissues

Answer 26

Distribution

Question 27

Factors that affect drug ABSORPTION

Answer 27

``` Formulation of Drug pH Gut Motility First Pass Metabolism Lipid Solubility ```

Question 28

Organ responsible for drug METABOLISM

Answer 28

LIVER

Question 29

Organ responsible for drug EXCERETION

Answer 29

KIDNEYS

Question 30

Factors that may impact the effect of the drug on the patient

Answer 30

``` Body Weight Age Sex Race Diet Genetic Factors ```

Question 31

Movement of drugs across biological membranes

Answer 31

Passive Transfer Carrier Mediated Transfer Endocytosis

Question 32

``` Simple diffusion (high to low concentration) Filtration through Aqueous pores ```

Answer 32

Passive Transfer

Question 33

Facilitated Diffusion | Active Transport

Answer 33

Carrier Mediated Transport

Question 34

Cells absorb external material by engulfing it with the cell membrane

Answer 34

Endocytosis

Question 35

What impacts the rate of DISTRIBUTION

Answer 35

Lipid Solubility Blood flow Ionization

Question 36

Biochemical Transformation First Pass _____ Liver

Answer 36

Metabolism

Question 37

``` Elimination of the drug - Renal - Fecal - Pulmonary - Glands Kidney ```

Answer 37

Excretion