Drug Table - Topoisomerase Inhibitors Flashcards Preview

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Flashcards in Drug Table - Topoisomerase Inhibitors Deck (16)
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1

Etoposide (Etopophos) class

Epipodophyllotoxins

2

Etoposide (Etopophos) mechanism

Inhibits topoisomerase II

3

Etoposide (Etopophos) Therapeutics

Testicular carcinoma, lung cancer, and
non-Hodgkin's lymphoma

4

Etoposide (Etopophos) other side effects

Dose-limiting myelosuppression
(neutropenia), oral mucositis

5

Teniposide (Vumon) Class

Epipodophyllotoxins

6

Teniposide (Vumon) Mechanism

Inhibits topoisomerase II

7

Teniposide (Vumon) Therapeutics

ALL

8

Teniposide (Vumon) Other side effects

Dose-limiting myelosuppression
(neutropenia), oral mucositis

9

Irinotecan (Camptosar) Class

Camptothecin
analogs

10

Irinotecan (Camptosar) Mechanism

Inhibits topoisomerase I

11

Irinotecan (Camptosar) Therapeutics

Advanced colorectal cancer; lung,
ovarian, cervical and brain tumors

12

Irinotecan (Camptosar) Other side effects

Severe neutropenia, severe
diarrhea

13

Topotecan (Hycamtin) Class

Camptothecin
analogs

14

Topotecan (Hycamtin) Mechanism

Inhibits topoisomerase I

15

Topotecan (Hycamtin) Therapeutics

Ovarian and small cell lung cancer

16

Topotecan (Hycamtin) Other side effects

Severe neutropenia, severe
diarrhea