Drugs Flashcards

1
Q

Anti-thrombin 3

A

Is a naturally anti-coagulant in your body

indirect 2a and 10a inhibitor

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2
Q

Fondaparinux

A

indirect 10a inhibitor
only SQ
used for prophylaxis

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3
Q

Rivaroxaban and Apixaban

A

Direct Xa inhibitor
Oral
don’t use AT3

Antidote: is adaxanet Alpha

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4
Q

Unfractionated/HMWH

A

only IV or SQ
must monitor labs
less risk of HIT
Reversed by protamine sulfate

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5
Q

Anticoagulants

A

Bivalirudin

Argatroban

Dabigatran Etexilate Mesylate

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6
Q

Warfarin

A

Is basically a competitive antagonist of Vitamin K epoxide reductase complex (VKORC1), blocks regeneration of reduced Vitamin K.

Warfarin’s effectiveness –> bleeding

Monitoring:INR

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7
Q

Anti-platelet Drugs

A

Aspirin: irreversible COX inhibitor

Low dose aspirin is the easiest/ cheapest way to prevent thrombosis and stop stroke

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8
Q

ADP receptor Inhibitors

A

Clopidogrel/prasugrel Irreversible ADP

Trigrelor: reversible ADP (P2Y) receptor antagonist

Glycoprotein 2b/3a inhibitors

Eptifibatide, Abciximab, Tirofiban

PDE inhibitors (dipyridamole)

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