Lectures 46 and 47

Question 1

Atherosclerosis process:

Answer 1

Fat deposits in arteries –> stenosis of the arteries –> less blood flow –> starves organs –> ischemia

Question 2

What is heart ischemia called?

Answer 2

angina

Question 3

Coronary Artery Disease

Answer 3

Coronary artery disease means narrowing/ blockage of coronary arteries

Question 4

What can coronary artery disease turn to

Answer 4

Acute Coronary Syndrome

Question 5

Myocardial Infarction

Answer 5

A sudden lack of blood flow to heart. Usually CAD becomes completely or partially occluded.

Permanent damage to heart

Question 6

Arteriosclerosis is when there are:

Answer 6

Atheroclerosis

Arteriolosclerosis

Monckeberg medial calcific sclerosis

Question 7

Atherosclerosis:

Answer 7

Atheromas ( fibrous fatty plaques)

Large and medium arteries

Atheromatous Plaque: fibrous cap and necrotic center

When a plaque ruptured the body is exposed to all contents and the subendothelial collagen –> stimulates platelet activation–> microthrombi

Question 8

Atherosclerosis Steps:

Answer 8

1. normal artery
2. endothelial disfunciton
3. fatty streak formation
4. stable plaque formation
5. unstable plaque formation

Question 9

What type of arteriosclerosis can hypertension cause?

Answer 9

It can cause hyaline arteriolosclerosis and hyper-plastic arteriosclerosis

Question 10

Hyaline Arteriolosclerosis

Answer 10

Early diabetics, hyaline thickening/narrowing of lumen. Highlighter pink

Question 11

Hyperplastic Arteriolosclerosis

Answer 11

Acute or severe increases in blood pressure, malignant HTN. Onion skin, lumen obliterated