Drugs Acting on the ANS

Question 1

promotes the action of the neurotransmitter acetylcholine

Answer 1

cholinergic drugs

Question 2

also called parasympathomimetic drugs because they produce effect that imitate parasympathetic nervous system

Answer 2

cholinergic drugs

Question 3

the 2 major classes of cholinergic drugs

Answer 3

• cholinergic agonists
• anticholinesterase

Question 4

2 major classes of cholinergic drugs

mimics the action of the neurotransmitter acetylcholine by directly stimulating cholinergic receptors

Answer 4

cholinergic agonists

Question 5

common cholinergic agonists

Answer 5

• acetycholine
• pilocarpine

Question 6

2 major classes of cholinergic drugs

inhibits the destruction of acetylcholine at the cholinergic receptor sites

Answer 6

anticholinesterase

Question 7

2 major classes of cholinergic drugs

what is the MOA of cholinergic agonists

Answer 7

works by mimicking the action of acetylcholine on the neurons in certain organs of the body

Question 8

cholinergic agonists stimulate the muscle and produce:

Answer 8

• salivation
• lacrimation
• urination
• defecation
• digestion
• decreased HR and RR
• constriction of pupils and bronchi
• vasodilation

Question 9

enzyme that breaks down acetylcholine

Answer 9

acetylcholinesterase

Question 10

2 major classes of cholinergic drugs

what is the MOA of anticholinesterase drugs

Answer 10

blocks the action of acetylcholinesterase at the cholinergic receptor sites

Question 11

2 categories of anticholinesterase

short duration of action

Answer 11

reversible anticholinesterase

Question 12

2 categories of anticholinesterase

long lasting and are used primarily as toxic insecticides, pesticides, or nerve gas; echothiopate-therapeutic usefulness

Answer 12

irreversible anticholinesterase

Question 13

cholinergic agonists are indicated for patients with ________, an auto-immune disorder causing less production of saliva

Answer 13

Sjogren’s syndrome

Question 14

cholinergic agonists are indicated for patients with glaucoma to __________

Answer 14

reduce eye pressure

Question 15

antocholinesterase are indicated for ________, an autoimmune disorder where the receptor sites are only a few

Answer 15

myasthenia gravis

Question 16

anticholinesterase drugs used to diagnose myasthenia gravis

Answer 16

• neostigmine
• endrophonium

Question 17

what is the MOA of cholinergic blocking drugs

Answer 17

blocks parasympathetic effects

Question 18

cholinergic blocking drugs are used to treat ________ or ________ conditions of the GI and urinary tracts

Answer 18

spastic; hyperactive

Question 19

cholinergic : ________; cholinergic blocking : spastic

Answer 19

atony

Question 20

most common cholinergic blocking drugs

Answer 20

atropine sulfate

Question 21

adrenergic drugs are also known as ___________

Answer 21

sympathomimetic drugs

Question 22

Adrenergic Drugs

classifications based on their chemical structure

Answer 22

• catecholamines
• noncatecholamines

Question 23

Adrenergic Drugs

classification based on how they act

Answer 23

• direct acting
• indirect acting
• dual acting

Question 24

Classifications of Adrenergic Drugs

drugs act directly on the organ innervated by the SNS

Answer 24

direct acting

Question 25

# Classifications of Adrenergic Drugs drug triggers the release of a neurotransmitter, usually norepinephrine

Answer 25

indirect acting

Question 26

# Classifications of Adrenergic Drugs drug has both direct and indirect actions

Answer 26

dual acting

Question 27

what is the MOA of adrenergic drugs

Answer 27

produce sympathetic effects by stimulating the alpha and beta receptors; mimic the action of norepinephrine or epinephrine

Question 28

common examples of catecholamines

Answer 28

* dopamine * epinephrine * norepinephrine

Question 29

catecholamines are potent inotropes, meaning __________

Answer 29

they increase the force of contraction of the heart

Question 30

# Adrenergic Drugs ________ stimulates organs but inhibitory in skeletal muscles

Answer 30

dopamine

Question 31

# Adrenergic Drugs indicated for nasal and eye decongestion

Answer 31

noncatecholamines

Question 32

# Adrenergic Drugs used to treat hypotension in cases of severe shock

Answer 32

noncatecholamines

Question 33

adrenergic blocking drugs are also called ___________

Answer 33

sympatholytic drugs

Question 34

what is the MOA of adrenergic blocking drugs

Answer 34

disrupts sympathetic effects; antagonize epinephrine

Question 35

classifications of adrenergic blocking drugs

Answer 35

* alpha-adrenergic blockers * beta-adrenergic blockers

Question 36

what is the MOA of alpha-adrenergic blockers

Answer 36

occupy alpha receptor sites on the smooth muscle of the blood vessels preventing catecholamines from occupying and stimulating the receptor sites

Question 37

________ is indicated for Raynaud's disease, a peripheral vascular disorder

Answer 37

alpha-adrenergic blockers

Question 38

why are alpha-adrenergic blockers indicated for pheochromocytoma

Answer 38

pheochromocytoma is the enlargement of the adrenal gland causing excessive production of adrenaline

Question 39

most widely used adrenergic blockers

Answer 39

beta-adrenergic blockers