Neurochemical changes in Major Depressive Disorder
- ⬇️ Serotonin
- ⬇️ Dopamine
- ⬇️ Norepinephrine
- ⬇️ SHIAA (suicide and aggression) = desinhibited ➡️ acting out
Chronic (least 2 yrs), mild depressed mood (distimia), functional.
Persistent Depressive Disorder
Alternating episodes of distimia and hypomania by 2 yrs
Which are the subtypes of bipolar disorder? Which is more functional?
- Bipolar I: Mania and Major depression
- Bipolar II: Hypomania episodes and Major depression. Better function.
Neurochemical changes in Bipolar Disorder
- ⬆️ Norepinephrine
- ⬆️ Serotonin
Mortality rate and cause of mortality in anorexia nervosa
- 5 to 18%
- Heart disease by Hipokalemia
Neurochemical changes in postraumatic stress disorder
⬆️ Norepinephrine and Epinephrine
What type of schizophrenia is more hard to treat?
Type II - Negative symptoms
Atypical antipsychotics (Risperidone, Olanzapine, etc)
Associated to muscarinic receptors
Type of personality: believe that is a very important person in his job, feel so anger and surprised when their subjects don’t make what he says, and has depressed mood, anhedonic, and insomnia since 2 weeks ago.
Main Dx criteria for Bipolar Disorder