Duffy Blood Group System

Question 1

What is the gene responsible for FY antigens and on what chromosome is this located?

Answer 1

ACKR1 located on chromosome 1

Question 2

What are the 5 FY system antigens?

Answer 2

1. Fya
2. Fyb
3. Fy6
4. Fy3
5. Fy5

Question 3

Which of the 5 FY antigens are destroyed by proteolytic enzymes?

Answer 3

Fya, Fyb, Fy6

Question 4

Which of the FY antigens are resistant to proteolytic enzymes?

Answer 4

Fy3 and Fy5

Question 5

What are the 4 FY system phenotypes?

Answer 5

1. Fy (a+b-)
2. Fy (a+b+)
3. Fy (a-b+)
4. Fy (a-b-)

Question 6

Which of the FY system phenotypes is resistant to Malaria, lack Fy3 and Fy6 and produces anti-Fy3?

Answer 6

Fy (a-b-)

Question 7

What FY system antigen is a specific receptor to Plasmodium?

Answer 7

Fy6