Lewis Blood Group System

Question 1

Alleles of the Le locus

Answer 1

Le (FUT3)
le

Question 2

What are the 2 Le antigens

Answer 2

1. Le a
2. Le b

Question 3

What are the 3 LE phenotypes?

Answer 3

1. Le (a-b-)
2. Le (a+b-)
3. Le (a-b+)

Question 4

May occur as the only antibody, usually IgM and clinically insignificant

Answer 4

Anti-Lea

Question 5

Seen as a less avid antibody and may be found with anti-Lea

Answer 5

Anti-Leb

Question 6

These individuals may transiently appear as Le(a-b-) and can produce LE antibodies

Answer 6

Pregnant women