MNS Blood Group System Flashcards
(13 cards)
How many antigens are there in the MNS blood group system
49
What are the two genes responsible for the MNS blood group system
- GYPA
- GYPB
Gene that produces glycophorin A which carries the M and N antigens
GYPA
Gene that produces glycophorin B which carries the S and s antigens
GYPB
What are the MNS antigens (1-4)
- M
- N
- S
- s
Demonstrates serine and glycine on the 1st and 5th positions respectively
M antigen
Demonstrates leucine and glutamic acid on the 1st and 5th positions respectively
N antigen
Demonstrates methionine at the 29th position
S antigen
Demonstrates threonine at the 29th position
s antigen
Lacking all or part of GPA due to exon deletion thus lacking M and N antigens
En a
Lacking S, s, and U antigens due to GYPB deletion
S- s- U-
Lacking all MNS antigens due to Mk gene
MkMk