EC Quiz Flashcards

1
Q

Name a few causes of cellular injury

irreversible injury to a cell leads to

A

chemical factors, ischemia, physical factors, genetic factors, immune reactions, nutritional factors

necrosis or apoptosis (cell death)

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2
Q

Apoptosis Vs Necrosis

Cell size, plasma membrane, adjacent inflammation

A

A: reduced cell size, plasma membrane is intact with altered structure, no adjacent inflammation
N: enlarged swelling of cell, plasma membrane is disrupted, frequent adjacent inflammation

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3
Q

Types of necrosis

A

coagulation, caseous, liquefactive, fatty, fibronoid

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4
Q

Types of reversible cell injury
and their causes (5)

A

atrophy: caused by lack of use or stress
hypertrophy: high BP
hyperplasia: imbalance of estrogen and progesterone
metaplasia: smoking
inter/intracellular cellular accumulation

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5
Q

Coagulation is a form of ______ caused by ____

what is it

A

necrosis, ischemia (lack of blood supply)

formation of a blood clot

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6
Q

What is a fibrinoid

A

A type of necrosis that is caused by trauma in blood vessel wall

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7
Q

fibrinolysis

fibrinogen

fibrin

ogin

A

the breakdown of fibrin in blood clots

a protein involved in forming and blood clot, made in the liver and forms fibrin

main protein in a blood clot that that helps stop bleeding and heal wounds

precursor

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8
Q

What makes cortisol

what is the purpose of cortisol

too much cortisol -
too little cortisol -

A

adrenal glands

body’s main stress hormone, control of sleep wake cycle and appetite

Cushing syndrome (weight gain and fatigue)
addison’s disease (weight loss and fatigue)

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9
Q

What secretes growth hormone

the 2 types of hyper growth hormone (compare and contrast onset)

the hormone that manages the effects of growth hormone the body

A

anterior pituitary gland

gigantism: childhood
acromegaly: adulthood

IGF - 1

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10
Q

Angina is ……., this has to do with …..

episodes of angina can be?

dyspnea

claudication

A

referred chest pain or discomfort, acute ischemic heart disease

silent

shortness of breathe

muscle pain due to lack of oxygen that is triggered by activity (peripheral ischemic response)

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11
Q

Stable angina

Unstable angina

angina is most common in?

A

Pain lasts a few minutes and occurs in a pattern, such as during exercise or stress.

Pain can be stronger or last longer than stable angina and does not follow a pattern.

woman

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12
Q

For cardiac concept the lower the heart rate the greater the _____ time this helps with

preload (EDV) is influenced by (4)

static standing is not good for the blood flow so what can solve that

A

filling
cardiac output

valves
vasoconstriction
respiratory pump
muscle pump

marching in place

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13
Q

EDV
ESV

If HR is 120 bpm how many seconds to fill up
60 bpm

flow rate

the less ___ remaining the greater the efficiency

Most common

Most deadly

A

after ventricle fills
after ventricle ejects blood

0.5
1

speed of flow back into the heart

ESV

diastolic

systolic

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14
Q

contractility of the heart

contractile strength is independent of

A

the relative ability of the heart to eject a stroke volume at a given afterload and preload

volume

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15
Q

Equation for EF (ejection fraction)

what is a good percentage

A

EDV-ESV / EDV x 100
120-40 = 80 /120 x 100 = 66.7% ejected

50-80 is normal
less than 50 is not good

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16
Q

Ischemic cascade

what does ^ include

A

diastolic dysfunction

impaired systolic emptying
ECG changes
muscular changes (myocardium)

17
Q

Signs of heart failure

what should be done with a pt with heart failure

A

rapid breathing
rapid heart rate
fatigue
light headedness

marches, bike rather than treadmill, deep breathing, lots of breaks

18
Q

Causes of heart failure
etiologic
risks
it is more common in

A

e: MI HTN
r: obesity pregnancy DM
woman

19
Q

Echocardiogram

A

uses sound waves to show how blood flows through the heart and heart valves

20
Q

Clinical manifestations of heart failure
left ventricle
right ventricle

A

L: progressive dyspnea
pulmonary edema
fatigue
R: nausea
weight gain
dependent edema

21
Q

Medical management of heart failure

A

Pharmacologic: decrease afterload
increase venous return/ preload
increase contractility

physical activity / nutrition

surgery

22
Q

Typical angina
atypical

A

A: at rest,
Typical: only get pain if you are exercises