E.Coli Flashcards
What is E.Coli?
- Gram Negative Faculative anerobic rod shaped bacterium
- 4500-5500 genes
- They frequently carry plasmids
- Zoonotic
- Economically important pathogen in humans and livestock
What is colonisation?
presence of a microorganism in a host but without any interaction between the host and the organism?
Why is E.Coli Pink on a MacConkey agar plate
E.Coli is lactose fermenting
What are strains of E.Coli Classified into?
Pathotypes
Name 5 determinants of E.Coli Virulence
- Fimbriae/ Flagella
- Outer Membrane Proteins
- Plasmids
- Acid Resistance
- Serum Resistance
What are some features Enteropathogenic Bacteria (EPEC)
Pedestals with long fimbriae
What are three diseases caused by ETEC? (Enterotoxigenic E. coli)
Colisepticaemia, Watery mouth, Neonatal diarrhoea (white scours)
What are the two toxins that ETEC contains?
- Heat labin toxins
- Heat stable toxins
Why would different ETECs have different susceptabilities over time?
Receptors of the fimbriae change over time
What are three diseases Extra Intestinal E.coli causes?
- Coliform mastitis
- Colisepticaemia
- Meningitis
What does APEC effect predominantly?
- affects young birds, predominantly 4-12 weeks old
What are some determinants of the APEC virulence?
- Fimbriae
- Flagella
- Serum resistance
- Acid resistance
What are some pre-disposing factors for avian colisepticaemia?
- Stress
- Husbandry practices
- Build up of ammonia
- Mycoplasmal infections
What are some features of Verotoxigenic E.Coli?
- Most strains are motile
- Most strains are non-sorbitol fermenters
- They harbour stx toxins
- harbour large virulence plasmids
What do Vero-Toxigenic diseases look like in pigs?
- Oedema disease
- Sudden death
- Oedema of the forehead, eyelids, stomach wall and larynx
- Ataxia, paralysis and convulsions
