Embryology: Back & Shoulder Flashcards
(33 cards)
mesoderm
formed during gastrulation, gives rise to lateral plate mesoderm, intermediate mesoderm, and paraxial mesoderm
paraxial mesoderm–>
somitomeres–> somites
lateral plate mesoderm
bones- limbs, sternum
dermis- neck, trunk, and limbs
intermediate mesoderm
urogenital system
somitomeres
primordium of somites
somitogenesis
paraxial mesoderm–> somitomeres–> somites
sclerotome
Origin: core of somites
Comp: mesenchyme (embryonic connective tissue)
Dest. vertebrae, ribs, and annulus fibrosus
mesenchyme
embryonic connective tissue, formed by all 3 germ layers; arise from somites of mesoderm
dermatome
Origin: dorsal region of the somite
Comp:
Dest.: deep surface of back, dermis
myotome
Origin: dorsomedial edge of somites
Comp:
Dest.: myoblasts that give rise to skeletal muscles of neck, trunk, and limbs
nucleus pulposus
notochord > mesoderm
annulus fibrosus
sclertome> somite> somitomere> paraxial mesoderm
myoblasts
myotome > somite > paraxial mesoderm
epaxial
dorsal region of myotome
hypaxial
ventral region hypaxial myoblasts > myotome
DPR
dorsal primary rami, innervate epaxial myoblasts that give rise to intrinsic back muscles
VPR
ventral primary rami, innervate hypaxial myoblasts that give rise to muscles of the lateral trunk, limbs, ect.
limb buds
outer layer: surface ectoderm
inner layer: parietal lateral plate mesoderm
proximal-distal axis
growth from the bud to the tip of the limb bud
Signaling: AER apical ectodermal ridge
preaxial-postaxial axis
postaxial structures: ulna and 5th digit
preaxial structure: radius and pollex
dorsal-ventral axis
anterior-posterior direction in adults
signaling: surface ectoderm sleeve
apical ectodermal ridge
a region of surface ectoderm that induces differentiation in underlying mesenchyme (according to the Progress Zone model)
zone of polarizing activity
a mesenchymal region on the post-axial margin of the limb bud signals development of the pre-post axial limb pattern
hand and foot plates
terminal portion of limb buds
digital rays: condensations of limbs
apoptosis separates the digits (except in ducks)