Flashcards in Endocarditis Deck (30)
What is meant by bacteraemia?
Presence of bacteria in the bloodstream
What temperature are blood cultures kept at?
The presence of bacteraemia is diagnostic of endocarditis. True/False?
Just indicates that there is infection somewhere in the body, or that samples may be contaminated
What is the commonest coagulase -ve Staph organism?
What does Staph epidermidis commonly contaminate?
What is infective endocarditis?
Infection of the heart valves
What are the commonest factors that predispose to endocarditis?
IV drug users
What is the general pathogenesis of endocarditis?
Damaged heart valves produce turbulent flow over irritated endothelium, causing platelet/fibrin deposition upon which bacteria settle, producing vegetation over the valve
Which organism is the most common cause of native valve endocarditis?
Which organism is the 2nd commonest cause of native valve endocarditis?
Name some atypical organisms that cause endocarditis
Gram -ve organisms
What are some symptoms of acute endocarditis?
What are some signs of endocarditis?
Roth spots, Janeway lesions, Osler nodes
What are roth spots?
What are Janeway lesions?
Nodular haemorrhagic lesions on palms and soles
What are Osler nodes?
Painful red lesions on palms and soles
How many blood cultures are taken for diagnosis of endocarditis?
If 3 blood cultures are taken and only 1 comes back positive, what might have been the cause?
Transthoracic echo is more effective than transoesophageal echo. True/False?
What organisms are usually responsible for prosthetic valve endocarditis?
Endocarditis in IV drug users predominately affects which side of the heart?
Right side (tricuspid valve)
How does Staph aureus endocarditis produce pneumonia?
Vegetation lodges in pulmonary circulation, causing inflammation, infection and abscess
Which antibiotics are given for native valve endocarditis?
Which antibiotics are given for prosthetic valve endocarditis?
Which antibiotic is given for IV drug user endocarditis?
Which antibiotics are given for MRSA endocarditis?
Which antibiotics are given for Strep viridans endocarditis?
Which antibiotics are given for Enterococcus endocarditis?
Which antibiotics are given for Staph epidermidis endocarditis?