Endocrine Flashcards

(36 cards)

0
Q

What are the functions of the endocrine system?

A
  • regulates metabolism
  • regulates fluid & electrolytes
  • counteract effect of stress
  • regulates growth
  • regulates reproduction
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1
Q

What are the major endocrine glands?

A
Pineal gland
Pituitary gland
Thyroid gland
Thymus
Adrenal gland
Pancreas
Ovary (female)
Testes (male)
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2
Q

Define endocrine.

A

Hormone released into the bloodstream

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3
Q

Define autocrine.

A

Hormone acts on the same cell that releases it

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4
Q

Define paracrine.

A

Hormone released into surrounding tissue rather than bloodstream. Eg interstitial fluid

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5
Q

Give an examples of amines

A

Catecholamines

Thyroid hormones

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6
Q

Give examples of proteins and peptides.

A

Insulin
Calcitonin
Oxytocin
GH

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7
Q

Give examples of steroids.

A

Mineralocorticoids
Glucocorticoids
Gonadocorticoids

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8
Q

What hormones does the anterior pituitary release?

A
  • Thyroid Stimulating Hormone
  • Adrenocorticotrophic Hormone (ACTH)
  • Follicle Stimulating Hormone (FSH)
  • Luteinising Hormone (LH)
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9
Q

What hormones are produced in the posterior pituitary?

A

ADH

Oxytocin

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10
Q

What cells produce glucagon?

A

Alpha cells in the pancreas

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11
Q

What cells produce insulin?

A

Beta cells in the pancreas

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12
Q

What cells produce pancreatic peptide?

A

Gama cells

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13
Q

What cells produce somatostatin?

A

Delta cells in the pancreas

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14
Q

What are the two thyroid hormones?

A

T3 Tri-iodo Thyroxine

T4 Thyroxine

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15
Q

Give examples of target cells for hormones.

A

Specific receptors within:
Plasma membrane
Cytoplasm
Nucleus

16
Q

Give examples of secondary messengers.

A

Intracellular enzymes
Calcium
Intracellular lipids

17
Q

Where do secondary messengers act?

A

On signal transcription of genes

18
Q

What are 3 patterns of gland secretion?

A

Endocrine
Autocrine
Paracrine

19
Q

What is a hormone?

A

A messenger chemical that is secreted all over the body and are associated with a longer effect over time…

20
Q

Why are hormones secreted?

A

In response to…
Levels in blood eg glucose
Other hormones eg pituitary
Directly stimulated by nerves eg oxytocin, adrenaline and noradrenaline

21
Q

What is the mode of physiological communication?

A

Stimulus - First Messenger (NT/Hormone) - Target (Receptors/Enzymes) - Intracellular Secondary Messenger - Response

22
Q

What responses can secondary messengers trigger?

A

Transcription of genes

Production of proteins

24
Q

What path operates on positive feedback?

A

Oxytocin and childbirth pathway

25
What is the hypothalamus?
Regulates activity if endocrine system | Exerts direct neural control...
26
Where does the hypothalamus act?
Directly on the anterior and posterior lobe of the pituitary gland.
27
What hormones are secreted by a anterior pituitary gland?
Growth hormone
28
What patterns of interaction?
Antagonististic Synergistic Permissive
29
Which region of the adrenal cortex produces..
X3
30
What is the normal range of blood glucose?
3.5 - 6.8mM
31
What is glucagon?
Secreted in response to low glucose levels and increases blood glucose levels by stimulating the breakdown of glycogen stored in liver and skeletal muscle
32
Define hypoglycaemia.
Low blood sugar levels
33
Define hyperglycaemia.
High sugar levels
34
Define type 1 Diabetes Mellitus.
No secretion of insulin
35
Define type 2 Diabetes Mellitus
Insufficient insulin secretion or resistance to secreted insulin
36
Negative feedback
??