Endocrine Flashcards
(36 cards)
What are the functions of the endocrine system?
- regulates metabolism
- regulates fluid & electrolytes
- counteract effect of stress
- regulates growth
- regulates reproduction
What are the major endocrine glands?
Pineal gland Pituitary gland Thyroid gland Thymus Adrenal gland Pancreas Ovary (female) Testes (male)
Define endocrine.
Hormone released into the bloodstream
Define autocrine.
Hormone acts on the same cell that releases it
Define paracrine.
Hormone released into surrounding tissue rather than bloodstream. Eg interstitial fluid
Give an examples of amines
Catecholamines
Thyroid hormones
Give examples of proteins and peptides.
Insulin
Calcitonin
Oxytocin
GH
Give examples of steroids.
Mineralocorticoids
Glucocorticoids
Gonadocorticoids
What hormones does the anterior pituitary release?
- Thyroid Stimulating Hormone
- Adrenocorticotrophic Hormone (ACTH)
- Follicle Stimulating Hormone (FSH)
- Luteinising Hormone (LH)
What hormones are produced in the posterior pituitary?
ADH
Oxytocin
What cells produce glucagon?
Alpha cells in the pancreas
What cells produce insulin?
Beta cells in the pancreas
What cells produce pancreatic peptide?
Gama cells
What cells produce somatostatin?
Delta cells in the pancreas
What are the two thyroid hormones?
T3 Tri-iodo Thyroxine
T4 Thyroxine
Give examples of target cells for hormones.
Specific receptors within:
Plasma membrane
Cytoplasm
Nucleus
Give examples of secondary messengers.
Intracellular enzymes
Calcium
Intracellular lipids
Where do secondary messengers act?
On signal transcription of genes
What are 3 patterns of gland secretion?
Endocrine
Autocrine
Paracrine
What is a hormone?
A messenger chemical that is secreted all over the body and are associated with a longer effect over time…
Why are hormones secreted?
In response to…
Levels in blood eg glucose
Other hormones eg pituitary
Directly stimulated by nerves eg oxytocin, adrenaline and noradrenaline
What is the mode of physiological communication?
Stimulus - First Messenger (NT/Hormone) - Target (Receptors/Enzymes) - Intracellular Secondary Messenger - Response
What responses can secondary messengers trigger?
Transcription of genes
Production of proteins
What path operates on positive feedback?
Oxytocin and childbirth pathway