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Flashcards in Endocrine Deck (37):
1

AM hyperglycemica triggered by insulin related hypoglycemia

somogyi effect

2

AM hyperglycemia triggered by physiological release of cortisol growth hormone and catecholamines

dawn phenomenom

3

what are increased levels of beta-hydroxybutyrate diagnostic of?

DKA

4

what is sipple syndrome

MEN2a hyperparathyroid, medullarly thyroid chancer, pheo

5

2 hormones released by the posterior pituitary

oxytocin and ADH

6

stimulates testosterone production in men and ovary estrogen and progesterone production in women

LH

7

spermatogenesis in men and develops ovarisn follicle in women

FSH

8

tx for prolactinoma

dopamine agonists (cabergoline, bromocriptine) (caber is better tolerated)

9

deficiency of vasopressin that causes increased thirst and large quantities of urine with low specific gravity

Diabetes insipidus

10

common med that causes diabetes insipidus

lithium

11

Tx for diabetes insipidus

Desmopressin

12

Ectopic production of vasopressin that causes excessive vasopressin/ADH. Hyponatremia.

SIADH

13

Tx of SIADH

d/c hypotonic fluids, restric free water. if bad hypertonic NaCl

14

autoimmune disorder with autoantibodies to TSH associated with pernicious anemia, myasthenia gravis, DM, addison's, celiac disease

Graves' disease

15

Type of thyroid cancer associated with MEN type 2

medullary carcinoma

16

tumor marker in medullary carcinoma of the thyroid

calcitonin

17

what does parathyroid hormone do?

increases serum calcium, decreases serum phosphorus

18

What does PTH do in the kidney

increaes Vit D, increases calcium reabosprtion. Decreas reabsorption of phosphate and bicarb

19

bones, stones, abdominal groans, psychic moans and fatigue overtones

hyperparathyroidism

20

presents with tetany, muscle cramps, paresthesias around mouth and hands.

hypoparathyroidism

21

what will DTRs be like with hypoparathyroidism

hyperactive DTRs

22

labs with hypoparathyroidism

low serum calcium, high serum phosphate

23

Tv for hypoparathyroidism

IV calcium gluconate, oral calcium

24

2 drugs that reduce serum vitamin D levels

phenytoin, phenobarbital

25

what lab is increased in osteomalacia

ALP (alk phos)

26

tx for paget's disease of the bone

bisphosphonates, calcitonin

27

hypertension, hypokalemia and weakness.

primary aldosteronism

28

tx for primary aldosteronism

spironolactone, eplerenone, or adrenalectomy

29

glucocorticoid excess from excess ACTH secretion from a pituitary tumor

Cushing's disease

30

nonpituitary neoplasm that can cause cushign syndrome

small cell carcinoma

31

only cause of cushing syndrome that has low ACTH due to negative feedback

adrenal tumor (adenoma)

32

test for addison's disease

cosyntropin stimulation test

33

has hyponatremia, hyperkalemia, low cortisol levels and increased ACTH

addison's disease

34

noctural hypoglycemia which causes reactive morning hyperglycemia

somogyi effect

35

tx for somogyi effect

decrease amount of bedtime insulin

36

on awakening cortisol rise causes hyperglycemia

dawn phenomenon

37

tx for dawn phenomenon

increase in bedtime insulin