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Flashcards in Heme Deck (20):
1

med that reduces frequency of sickle cell crises

hydroxyurea

2

what are the 3 encapsulate bacterium(individuals with surgical splenectomy or sickle cell are at increased risk)

Pneumococcus, N meningitits, h flu

3

when does heparin related thrombocytopenia occur

501- day safter therapy

4

which laboratory test assess teh intrinsic coagulation pathway

partial thromboplastin time (apTT)

5

malignancies commonly associated with superior vena cava syndreom

non-hodgkin's lymphoma and small cell carinoma of the lung

6

lab test for extrinsic coagulation pathway

prothrombin time

7

what is the final strep in clotting

converison fo fibrinogen to fibrin

8

MOA for dabigatran

direct rhrombin inhibitor (inhibits production of fibrin)

9

philadelphia chromosome is associated with what?

chronic myelogenosu leukemia

10

cause of pernicious anemia

destruction of pariteal cells in the stomach

11

common symptom in individuals with sickle cell trait in extreme conditions

painless hematuria/ rhabdo at high altitudes

12

hemolytic anemia + elevated LDH suggest what

TTP

13

punched out lytic lesions often found in spine

multiple myeloma

14

young patients which repeated aplastic crisis with spherocytosis should receive what?

splenecomty

15

diagnosis of malaria

demonstration of hte parasite in stained peripheral blood smears

16

Does ITP cause hemolysis?

no, but TTP does

17

bite cells are characteristic of what?

G6PD deficiency

18

Auer rods and pathognomonic for what?

AML

19

tx for Von Willebrand dz

vasopressin nasal spray (DDAVP) (also treats Factor VIII)

20

best test to confirm an immune mediated hemolytic anemia

Coombs test (direct- antibody on red cell membrane) indirect is antibody in the serum