endocrine disease (parathyroid, acromegaly, DI) Flashcards

1
Q

effects of PTH

A
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2
Q

primary hyperparathyroidism

A

functional parathyroid adenoma
middle aged dogs, keeshonds
C/S: PU/PD, weakness, urinary tract signs
dx- high Ca, low P, isosthenuia/hyposthenuria, calcium oxalate stones, UTI
neck U/S, PTH levels NORMAL (should be low), negative PTHrp

tx- sx, heat/ethanol ablation

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3
Q

feline hypercalcemia causes

A

neoplasia (lymphoma, SCC, retrovirus), renal disease, idiopathic

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4
Q

idiopathic hypercalcemia (cats)

A

anorexia, lethargy, v+/d+, PU/PD, neuro signs

tx- alendronate, bisphosphonate 5-10mg q7d

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5
Q

secondary hyperparathyroidism

A

renal or nutritional (low Ca/P)

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6
Q

hypoparathyroidism

A

lymphocytic parathyroiditis (atrophy), trauma

poodles, mini schnauzers, middle aged

C/S- abrupt intermittent neuro signs (facial rubbing, twitching, seizures

dx- ECG- bradycardia, chem (low Ca, high P)

tx- diazepam for tetany, ca gluconate, calcitriol, ca carbonate

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7
Q

DDX for hypocalcemia

A

low mg, ethylene glycol, CKD, hypo ALB, pancreatitis, GI disease

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8
Q

acromegaly

A

bone/tissue growth, insulin resistance-> pituitary somatotroph adenoma (GH secretion)

C/S- big head/chin, resistant DM, HCM, joint changes, neuro signs

dx- glucosuria, high BG, MI
tx- radiation, sx

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9
Q

diabetes insipidus

A

central- idiopathic, congenital, rare (young)
lack of ADH-> Pu/PD
dx- r/o other causes (addisons, cushings, thyroid etc), USG <1.010, modified water deprivation test-> if USG increases-> psychogenic PD, if not CDI

nephrogenic- renal disease, toxins, hypercalcemia, pyometra

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10
Q
A
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