endocrine system Flashcards

1
Q

endocrine

A

targets a distant cell throughout bloodstream

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2
Q

exocrine

A

secretes enzymes into ducts

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3
Q

paracrine

A

targets nearby cell

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4
Q

autocrine

A

targets itself

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5
Q

peptide hormones

A

bind to surface cell membrane receptor –> receptors start cell signaling pathways via secondary messengers

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6
Q

steroids

A

diffuse plasma membrane and bind receptor in cytoplasm –> hormone + receptor is transported into nucleus to act transcriptionally

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7
Q

tyrosine derivatives

A

thyroid hormones : lipid-solube, bind to receptors in nucleus, and require protein carrier in blood
catecholamines: water-soluble, bind receptors on target tissue, and mainly act via secondary messenger cAMP

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8
Q

secondary messengers

A
  • small molecules that pass along signals
  • initiated by ligand-receptor binding
  • amplify signal strength to target molecules in the cytoplasm or nucleus
    examples: IP3, cAMP, calcium, DAG
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9
Q

hypothalamus

A
  1. secretes releasing hormones to anterior pituitary gland
  2. APG responds by secreting hormones
  3. hypothalamus secretes ADH and oxytocin to be stored in the posterior pituitary gland
  4. PPG stores ADH and oxytocin for release

ADH ——> kidneys
oxytocin ——> uterus/mammary gland

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10
Q

ACTH

A

stimulates adrenal cortex –> releases glucocorticoids

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11
Q

TSH

A

stimulates thyroid gland to release thyroid hormones

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12
Q

LH

A
  • stimulates corpus luteum formation in girls
  • stimulates interstitial cells of tests to produce testosterone
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13
Q

FSH

A

in women: stimulates maturation of ovarian follicles to secrete estrogen
in men: stimulates seminiferous tubule maturation and sperm production

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14
Q

hGH (somatropin)

A

stimulates bone and muscle growth

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15
Q

prolactin

A

stimulates milk production

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16
Q

posterior pituitary

A
  • does not synthesize hormones
  • stores ADH and oxytocin for release
17
Q

ADH (vasopressin)

A

increases reabsorption of water by increasing permeability of nephron’s collecting duct

18
Q

oxytocin

A

increases strength of uterine contractions; stimulates milk ejection; induces maternal behavior

19
Q

pancreas

A
  • glucagon
  • insulin
  • somatostatin
20
Q

glucagon

A
  • secreted by Alpha cells, released when energy levels are low
  • increased glucose levels in the blood
  • stimulates liver to convert glycogen to glucose
  • stimulates gluconeogenesis in liver
  • converts stored adipose tissue into blood lipids
21
Q

insulin

A
  • secreted by Beta cells
  • anabolic, released when energy levels are high
  • decreases glucose levels in blood
  • stimulates liver and muscle to store glucose as glycogen
22
Q

somatostatin

A
  • secreted by Delta cells
  • inhibits release of insulin and glucagon
  • increases nutrient absorption time by decreasing digestive system flow
23
Q

epinephrine and norepinephrine

A

adrenal medulla
* fight or flight
* converts glycogen to glucose (increase blood level glucose)
* vasoconstrictor to kidneys and bladder
* vasodilator to skeletal muscle, increased heartbeat
* bronchodilation
* prepares body for intense physical activity

24
Q

glucocorticoids (cortisol and cortisone)

A

adrenal cortex
* raise blood glucose levels
* degrades adipose tissue to use as energy

25
Q

mineralocorticoids (aldosterone)

A

adrenal cortex
* increases reabsorption of Na+ and excretion of K+ in kidneys
* causes passive reabsorption of water in nephron which raises blood pressure

26
Q

Which hormones are permeable to the cell membrane?

A

STEROID hormones
- cortisol
- aldosterone
- testosterone
- estrogen
- progesterone
TYROSINE-DERIVED
- thyroxine
- triiodothyrine

27
Q

hormones produced by thyroid

A
  • thyroxine
  • T3
  • calcitonin