Endocrine System Flashcards

(48 cards)

1
Q

Endocrine Grands

A

Synthesize and secrete chemical substances called hormones directly into the circulatory system

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2
Q

Exocrine Glands

A

Secretes substances transported by ducts (gallbladder)

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3
Q

Hypothalamus

A

The regulatory center of the endocrine system, part of the forebrain, located above the pituitary gland, secretes hormones, regulate the pituitary via negative feedback, ADH/oxytocin

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4
Q

Gonadotropin-releasing Hormone (GnRH)

A

Stimulates the anterior pituitary to secrete follicle-stimulating hormone FSH and LH

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5
Q

Hypophyseal Portal System

A

Releasing hormones can immediately reach the anterior pituitary without first entering the circulatory system

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6
Q

Thyrotropin-releasing hormone (TRH)

A

Stimulates the anterior pituitary to release thyroid hormones, T3 and T4

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7
Q

Growth hormone-releasing (GHRH)

A

Stimulates the anterior pituitary to release growth hormone

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8
Q

Pituitary Gland

A

Small, trilobed gland at the base of the brain, anterior and posterior, intermediate

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9
Q

Infundibulum

A

Connects the hypothalamus to the posterior pituitary gland

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10
Q

Anterior Pituitary

A

Synthesizes direct hormones and tropic hormones

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11
Q

Tropic Hormones

A

FSH, LH, ACTH, TSH

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12
Q

Follicle-stimulating (FSH)

A

Maturation of ovarian follicles, which in turn secrete estrogen, sperm production

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13
Q

Luteinizing Hormone (LH)

A

Stimulates ovulation and maintenance of the corpus luteum, regulating progesterone secretion, synthesizes testosterone

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14
Q

Adrenocorticotropic hormone (ACTH)

A

Stimulates the adrenal cortex for glucocorticoids

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15
Q

Thyroid-stimulating Hormone (TSH)

A

Stimulates the thyroid gland to synthesize and release thyroid hormones

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16
Q

Direct Hormones

A

Prolactin, Endorphins, Growth hormone, MSH

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17
Q

Prolactin

A

Stimulates milk production

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18
Q

Endorphins

A

Pain-relieving

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19
Q

Growth hormone (GH)

A

bone and muscle growth

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20
Q

Melanocyte-stimulating hormone (MSH)

A

Sun-inducing darkening of skin

21
Q

Posterior Pituitary

A

Does not synthesize hormones, stores and releases peptide hormones oxytocin and antidiuretic hormone

22
Q

Oxytocin

A

Uterine contractions, milk secretion

23
Q

Antidiuretic Hormone (ADH)

A

Increases water permeability in the collecting duct of the nephron, promoting water reabsorption and increasing blood volume, decreases blood osmolarity

24
Q

Adrenal Glands

A

Top of kidneys, adrenal cortex, adrenal medulla

25
Corticosteroids
Exert their action by determining which genes are transcribed in the nuclei of their target cells and at what rate
26
Glucocorticoids
Cortisol and cortisone, glucose regulation and protein metabolism, anti-inflammatory effects
27
Mineralocorticoids
Aldosterone regulates plasma levels of sodium and potassium, active reabsorption of sodium
28
Androgens
Male sex hormones
29
Epinephrine
Increases the conversion of glycogen to glucose in liver and muscle tissue, increase metabolic rate, fight or flight effect
30
Thyroxine (T4)
4 iodine atoms, formed and secreted by the thyroid gland
31
Triiodothyronine (T3)
Five times more potent than T4, Converted from T4
32
Hypothyroidism
Thyroid hormones are under secreted or not secreted at all, slowed heart rate, fatigue, weight gain
33
Hyperthyroidism
Overstimulated, increased metabolic, profuse sweating, weight loss
34
Parathyroid Glands
Four small pea-shaped structures embedded in the posterior surface of the thyroid, secrete PTH, regulate plasma Ca2+ concentration
35
Islets of Langerhans
Small glandular structures where endocrine function is performed (alpha,beta,delta) in Pancreas
36
Alpha cells
Produce and secrete glucagon
37
Beta cells
Produce and secrete insulin
38
Delta cells
Secrete somatostatin
39
Glucagon
Peptide hormone, released when blood glucose levels are low (Pancreas)
40
Insulin
Protein hormone, is secreted in response to high blood glucose concentrations
41
Somatostatin
Blocks the secretion of both insulin and glucagon from adjacent cells
42
Type 1 Diabetes
Less common, younger, presence of islet cell antibodies, autoimmune
43
Type 2 Diabetes
Most common, older, resistance to insulin, increased hepatic glucose production, obesity
44
Renin
An enzyme that converts the plasma protein angiotensinogen and angiotensin 1 in kidneys
45
EPO (erythropoietin)
Glycoprotein produced in the kidney that stimulates red blood cell production
46
Melatonin
Released by the pineal gland, base of brain, regulation of the circadian rhythms
47
Peptide Hormones
Amino acids, extracellular, stimulates a receptor, dissolves and travels freely, quick onset, short-lived
48
Steroid Hormone
Cholesterol, Intracellular, binds to a receptor, bound to a carrier protein, slow onset, long-lived action