Endometrial Cancer Flashcards Preview

OBGYN Clerkship > Endometrial Cancer > Flashcards

Flashcards in Endometrial Cancer Deck (12)
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1
Q

what is the penny, nicket, dime, quarter?

A

simple hyperplasia w/o atypia = 1% progression to cancer

complex hyperplasia w/o atypia = 3-5%

simple hyperplasia w/ atypia = 8-10%

complex hyperplasia w/ atypia = 25-30%

2
Q

what are risk factors to developing endometrial hyperplasia

A

increased E levels

tamoxofen, obese, PCOS/anovulation, nulliparity, early menarche and late menopause, granulosa cell tumors

3
Q

What are protective factors to developing endometrial hyperplasia

A

decreased E elevels/inc P levels

OCPs, multiparity, diet and exercise

4
Q

HNPCC/Lynch syndrome is high risk for what cancers

A

colon
endometrial
ovarian

**get annual endo bc > 35 yo

5
Q

what are the 2 types of endometrial cancers

%
race
Age
Pa

A

type I: E dept | 80% | white | perimenopausal | good px
**preceeded by hyperplasia

type II: E indept (papillary serous or clear cell) | 20% | black, asian | postmenopausal | bad

6
Q

Smx of endometrial cancer

A

postmenopausal or abnormal vaginal bleeding

7
Q

Management for abnormal bleeding suggestive of endometrial cancer

A

premenopausal = endometrial bc then proper tx

postmenopausal = US, if endometrial strip > 5mm get endometrial bx (if < 5mm, no further workup)

8
Q

differentiates stage I from II endometrial CA

II from III

A

II invades endocervix

III in nearby structures (serosa, vagina, pelvic LN)

9
Q

treatment for endometrial CA

A

TAHBSO
pelvic/paraaortic LNectomy
radiation (if high risk)

10
Q

Stage or grade more important for prognosis

A

grade

11
Q

what is the diff between G1, G2, and G3

A

G1 = 50% ‘’

12
Q

what are characteristics for high risk endocervical cancers

A
  • > 50% myometrial invasion
  • type 2 (papillary, serous, clear cell)
  • grade 3
  • stage III+
  • size > 2cm
  • LN+