Flashcards in Physiology of Pregnancy Deck (37)
What at what point does an embryo become a fetus
8 weeks (cardiac activity?)
Defn of grand multip
parity >/= 5
What is Charwicks sign
blue discoloration of cervix (early sign of preg)
What is goodell sign
softening of cervix (early sign of preg)
What is hegar/ladin sign?
softening of uterus
What is naegele's rule
EDC = LMP + 1yr -3m + 7d
What are indications for US
uncertain gestational age
pubic symphysis = __ wks
umbilicus = ___ wks
xiphoid process = ___ wks
How can heart sounds change in preg?
systolic murmur (2/2 inc BV)
What is avg materanl HR when baby is at term
how does BP change in preg
dec 2/2 to dec in scr (2/2 effecrts of progesterone/vasodil substances being produced)
acid base state in preg + why?
compensated repiratory alkalosis
Bohr effect, inc RR inc CO2 gradient to inc gas exchange with fetus
Tidal volume inc or dec in preg
increase (dec in FRC) (also dec FRC due to elevated diapragm)
What is the cause of morning sickness?
how do kidneys change in pregnancy?
they enlarge, ureters dilate (R>L), hydronephrosis, GFR increased by 50%
what causes ureters to dilate/hydronephrosis
progesterone and compression by enlarging uterus
is preg a hypercoagulable state?
yes! inc E2
why are preg women anemic
dilutional,there is an inc in plasma volume > inc RCV
** but still need inc Fe bc they are making more RBCs
What is the signaling for increased intravascular volume during pregnancy
inc renin --> inc angiotensin --> inc Na retention --> retain fluid to inc intravascular volume
when does hCG peak?
~10 weeks (doubles every 48 until this point)
What is responsible for maintianing fetal nutrition? Effects on mom?
hPL: inc maternal lipolysis and dec glc uptake by mom (anti-insulin effect) which allows for more glc to be available for fetus
--> mom in diabetogenic state with glucosuria and ketonuria
change in posture late in preg
Skin changes in preg? cause?
spider angiomata and palmar eryethema (2/2 inc E)
linea nigra and melasma/chlosasma (2/2 inc MSH)
How does PTH change in preg? Why?
increases, to cause inc Ca abs and vit D for growing fetal bones
changes in TSH, T3/4 during preg
transient dec TSH nc hCG is structurally similar to TSH tp the pit gland dec production
Total T3/4 increases because thyroid binding globilin increases, howevere free T3/4 remains normal
vits/minerals/diet changes needed in preg
inc kcal, folate, iron, vit C, omega 3 FA
dec vit A (teratogenic), calcium (still need but it chalates Fe)
what are braxton-hicks contractions?
irreg contractions w/o cervical dilation
how to manage GERD in preg
antacids , PPIs or H2 blockers if severe
What is round ligament pain + Tx?
shooting pelvic pain due to round ligament stretching, Tx is tylenol + warm compress