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Flashcards in Cervical Cancer Deck (15)
1

What HPV strain causes comon warts/verruca vulgaris

HPV 1, 2, 3, 4

2

What HPV strain causes genital warts/condyloma acuminata

HPV 6/11

3

HPV strain that cuase cervical cancer

HPV 16, 18, 31, 33, 45

4

What strains does guardasil protect against

6, 11, 16, 18

5

Who gets HPV

women 11-26
boys 11-12

**regular immunization given at 11 or 12

6

Management for ASC-US

HPV DNA testing
(-) : repeart pap in 1 yr
(+) : colpo and cervical Bx

7

2 types of cervical cancer

squamous cell carcinoma
atypical glandular cells

8

What are the indications for a diagnostic cone bx?

Microinvarion < 3mm
endocervical cuttage positive
discrepency of 2 steps (high grade pap, not confirmed on bx)
Inadequate culpo
Adenocarcinoma in situ

9

Diagnostic conde Bx complications

bleeding
infection
cervical stenosis
incompetent cervix
PROM
Preterm labor

10

What is CIN? MC timimg of developing CIN? MC location?

premalignant dz of cervical epithelium 2/2 HPV inf
during menses and after pregnancy
anterior lip of transformational zone, multifocal

11

CIN I vs II vs III def

I: dysplasia in basal 1/3 of epithelium
II: dysplasia in basal 2/3 of epithelium
III dysplasia in >2/3 to full epithelium

12

CIN I, II, III management

I: repeat pap q 6mo x 2 w/ LEEP if persistent for 2 yrs
II: LEEP
III: LEEP

13

management when HGSIL on pap but normal on Bx

diagnostic cone bx

14

Smx of cervical SCC

usualy smx, can present as post coital bleeding

15

What is TNM criteria for the following stages + Tx
0
1a
1b
2a
2b
3a
3b
4a
4b

0 : carcinoma in situ | simple hysterectomy pr cold knife cone

1a : cervix only, 7mm or visible lesion | radical hystorectmy or radiation

2a : involves upper 2/3 vagina, no parametrium | ''
2b : involved upper 2/3 vagina, parametrium | chemoradiation (external and internal radition + cisplatin)

3a : involves lower 1/3 vagina, no pelvic wall | ''
3b : involves lower 1/3 vagina, pelvic wall | ''

4a : local met (bladder or rectum) | "
4b : distal met | ''