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Term 4: Infectious Diseases > Enterobacteriacae > Flashcards

Flashcards in Enterobacteriacae Deck (54)
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1

What is MacConkey agar?

-contains bile salts to suppress the growth of most gram (+) organisms

-suppresses growth of Neisseria & Haemophilus

-also contains lactose & a pH indicator

2

What type of agar plates do we use to test lactose fermentation in Gm (-) organisms?

MacConkey agar

3

Which surface antigen on Gm (-) organisms confers motility?

Flagella

(H Antigen)

4

What do fibriae do for Gm (-) bacteria?

-allows attachment to host cell

-exhibit phase variation

(used for UTI)

5

What does it mean if bacteria can form a biofilm?

-they have a capsule

6

Why can't organisms that have lipooligosaccharide grow in the gut?

-sensitive to bile salts

7

What infection is caused by bacteria with P-fimbriae?

Pyelonephritis

8

What does LPS do to the host?

Activates the sepsis cascade

9

What are siderophores?

-allow Gm (-) bacteria to scavenge Fe from environment

-Gm (-) bacteria need iron to live

10

What is the K antigen a part of?

-the gram (-) capsule

11

What diseases are caused by Klebsiella?

-UTI

-Pneumonia

-multiple nosocomia infections (biliary infection, peritonitis, wound infxn)

12

When are Morganella and Providencia infections seen?

-individuals with long-term catheters

*very close cousins of Proteus

13

What diseases are caused by Proteus mirabilis?

-UTI

-Staghorn calculus

14

What diseases are caused by Citrobacter?

-Catheter associated UTI

-Brain abscess in neonates

15

What mediates adhesion of E. Coli to intestinal mucosa?

Fimbriae (Pili)

16

In what organism do we see Hemolytic uremia syndrome (HUS)?

-Enterohemorrhagic E. Coli (EHEC)

-Shigella

17

What are the three components of Hemolytic uremic syndrome?

-Renal failure

-Hemolytic anemia

-Thrombocytopenia

18

Pt has renal failure, hemolytic anemia, and thrombocytopenia. What organism are we thinking?

-Enterohemorrhagic E. Coli (EHEC)

-Shigella

* these are the components of Hemolytic uremic syndrome, seen in EHEC infection

19

What diseases are caused by Enteropathogenic E. Coli (EPEC)?

-acute diarrhea in infants

20

What diseases does Enteroaggregative E. Coli (EAEC) cause?

-chronic diarrhea & malnutrition in developing countries

-#2 travelers diarrhea

21

How do we identify Enteroaggregative E. Coli (EAEC)?

stacked brick adherence to tissue culture cells in Hep-2 cell assay

22

What diseases are caused by Enteroinvasive E. Coli?

diarrhea

23

E. coli only causes neonatal meningitis if it has ________.

K antigen

24

E. coli's heat Labile toxin increases c_MP.

cAMP

25

E. coli's heat Stable toxin increases c_MP levels.

cGMP

26

Lactose fermenters turn _________ on mackonkey agar.

Pink

27

What infections are caused by klebsiella?

-lobar pneumonia

-UTI

28

To treat klebsiella you need to use _________ because all klebsiella are ampicillin resistant.

B lactamase inhibitors

29

Is serratia a normal part of the human fecal flora?

no

30

A disk approximation test is used to see if there is ________ in __________ (bacteria).

-induced resistance

-Enterobacter