Do Non-fermenting Gram-negative bacteria (NFGNB) ferment sugars?
What are the Non-fermenting Gram-negative bacteria (NFGNB) (hospital acquired Gm-)?
-Pseudomonas -Stenotrophomas -Acinetobacter -Burkholderia
Where do NFGNB live?
-not in the GI tract -live in islands everywhere -cause lots of nosocomial infections -not typically found in nutrient rich areas
Which of the following persons is at highest risk for infection due to a non-fermenting Gram-negative bacillus? A. 19 year-old college student with meningitis B. 25 year-old man with a sexually transmitted disease C. 75 year-old man with nosocomial pneumonia after admission for a stroke D. 10 year-old boy with an ear infection E. 57 year-old man with bronchitis
C. 75 year-old man with nosocomial pneumonia after admission for a stroke
Why Do You Need To Suspect Pseudomonas?
-labs take 48 hours -If you are dealing with a Pseudomonas infection but do not institute effective treatment, the chance of your patient surviving go way down
Which of the following persons is at highest risk for infection due to Pseudomonas? A. 30 year-old football player with a boil B. 80 year-old women with community-acquired pneumonia C. 3 year-old boy with septic arthritis D. 23 year-old man with leukemia and neutropenic fever E. 65 year-old diabetic with otitis media
D. 23 year-old man with leukemia and neutropenic fever
What are the risk factors for stenotrophomonas infection?
-In light of low pathogenicity host factors are paramount in SM infection -Broad-spectrum antimicrobial use especially carbapenems will select for SM colonization -Malignancy (not only neutropenia) -Catheters -Prolonged ICU stay
Which of the following persons is at highest risk for infection due to Stenotrophomonas? A. 53 year-old neutropenic women status-post a stem-cell transplantation recently treated for pneumonia with a broad spectrum antibiotic B. 27 year-old man with AIDS and meningitis C. 37 year old alcoholic with pancreatitis and subsequent pancreatic abscess D. 23 year-old women with cystitis
A. 53 year-old neutropenic women status-post a stem-cell transplantation recently treated for pneumonia with a broad spectrum antibiotic
Which of the following persons is at highest risk for infection due to Acinetobacter? A. 57 year-old man with community-acquired pneumonia B. 27 year-old man with AIDS and meningitis C. 43 year-old man with catheter-related bacteremia after 2 week stay in an intensive care unit D. 80 year-old nursing home resident with post-influenza pneumonia
C. 43 year-old man with catheter-related bacteremia after 2 week stay in an intensive care unit
What is Cepacia syndrome and what causes it?
-Necrotizing granulomatous pneumonia with bacteremia & death -caused by Burkholderia
You are on your pediatric ward month and a 18 month old boy is admitted for fever. Blood cultures grow Burkholderia cepacia. What do you need to do?
Do a workup for chronic granulomatous disease
What risk factors increase risk for Burkholderia cepacia infection?
-Cystic fibrosis -Chronic granulomatous disease
Which of the following persons is NOT at significant risk for infection due to Burkholderia cepacia complex? A. 19 year-old women with cystic fibrosis and pneumonia B. 11 year-old boy with chronic granulomatous disease and pneumonia C. 37 year-old man with leukemia, neutropenia, and a bloodstream catheter infection D. 19 year-old women with cystic fibrosis and a urinary tract infection
D. 19 year-old women with cystic fibrosis and a urinary tract infection
What organism grows a blue-green colony on blood agar?
What infections are caused by Pseudomonas?
Burns Endocarditis Pneumonia Sepsis External malignant otitis media UTI Diabetic Osteomyelitis (BE PSEUDO)
What organism do you suspect in nosocomial infections in chronic granulomatous and cystic fibrosis patients?
What are the four W's of hospital aquired gram negative bacteria (NFGNB)?
Wind (pneumonia) Water (UTI) Wound Wires (IV lines)
What organism causes infections that smells like grapes?
What bug are we considering in children who develop osteomyelitis secondary to a puncture wound to the foot, usually a nail through a sweaty tennis shoe?
What two bugs are frequent causes of right heart valve endocarditis in IV drug users?
S. aureus Pseudomonas
What antibiotic does Stenotrophomonas love?