Enzymatic Inhibition Flashcards Preview

Biochemistry > Enzymatic Inhibition > Flashcards

Flashcards in Enzymatic Inhibition Deck (9)
Loading flashcards...
1
Q

what is irreversible inhibition?

A

bind permanently to enzyme, and enzyme must be replaced

2
Q

what is competitive inhibition?

A

inhibitor competes with the substrate

3
Q

what is uncompetitive inhibition?

A

inhibitor binds the enzyme-substrate complex, but not the enzyme alone

4
Q

what is noncompetitive inhibition?

A

inhibitor binds the enzyme or enzyme-substrate complex; slows or stops enzymatic process, and substrate binding is not affected

5
Q

what is mixed inhibition?

A

inhibitor binds enzyme or enzyme-substrate complex; affects substrate binding and enzyme function

6
Q

what happens to the kinetic curve in competitive inhibition?

A

no change in Vmax, Km moves right

7
Q

what happens to the kinetic curve in uncompetitive inhibition?

A

reduces Vmax, Km moves left

8
Q

what happens to the kinetic curve in noncompetitive inhibition?

A

reduces Vmax, no change in Km

9
Q

what happens to the kinetic curve in mixed inhibition?

A

reduces Vmax, Km moves right