epilepsy Flashcards

(41 cards)

1
Q

Epilepsy

A

tendency to have seizures in the absence of provocations that would cause the normal brain to have a seizure.

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2
Q

primary generalized seizure

A

a seizure that involves the entire brain at the same time. Consciousness is necessarily lost.

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3
Q

complex partial

A

a seizure of focal onset that involves areas that impair consciousness. The patient often appears dazed or confused and remembers only a part of the seizure (if at all).

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4
Q

myoclonic seizure

A

a brief generalized seizure that may be so brief as to produce a motor jerk (myoclonus) but no actual loss of consciousness.

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5
Q

petit mal seizure

A

a brief generalized seizure that interrupts consciousness but which does not result in motor symptoms (outside of, possibly, some eyelid fluttering). It may happen hundreds of times a day.

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6
Q

simple partial seizure

A

a seizure from portions of the cerebral cortex having very specific functions (i.e., motor, sensory, visual, olfactory, auditory), such that the auras are easily explained.

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7
Q

focal seizure

A

another name for a partial seizure. It arises from a specific seizure focus in the cerebral cortex. This may be a scar or an irritated area around a tumor or other cortical lesion.

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8
Q

secondary generalized

A

is the spread of a focal seizure to involve the entire brain.

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9
Q

status epilepticus

A

a medical emergency that consists of continuous or recurrent seizures over at least 30 minutes without waking up in between.

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10
Q

postictal period

A

a period of cortical depression following a seizure

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11
Q

interictal

A

the period between seizures

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12
Q

todd’s paralysis

A

a period of focal weakness after a seizure due to a prolonged postictal period in a region of cerebral cortex. This may give clues to the side and location of a seizure focus.

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13
Q

hippocampal sclerosis

A

scarring of the hippocampus. This is a common cause of temporal lobe epilepsy and occurs early in life. It is often associated with prolonged febrile convulsions in early childhood.

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14
Q

temporal lobe epilepsy

A

indicates an epilepsy with a seizure focus in the temporal lobe.

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15
Q

seizure focus

A

area of abnormal electrical excitability in the cerebral cortex.

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16
Q

prmary generalized seizures do not have

A

auras

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17
Q

geeralzied tonic-clonic seizures result in

A

autonomic upset (large pupils ,hyperthermia, tachycardia, salivation, emptying of bladder)

18
Q

petit mal & post ictal period

A

they have none

19
Q

status epilepticus

A

medical emergency-consists of continuous or recurrent seizures of 30 mins w/o waking up in between

20
Q

status epilepticus often due to

A

sedative withdrawal

21
Q

EEGs and seizure

A

2/3s of patents have abnormal activty even when not having seizure

22
Q

motor cortex seizure

A

Jacksonian (partal simple)

23
Q

complex partial are

A

limbic seizure

24
Q

later childhood–>adolescence main type of seizures

A

temporal lobe epilepsy

juvenile myoclonic epilepsy

25
very young children main types of seizures
petit mal | metabolic defect/congenital malformations
26
triggers for grand mal seizures
outside of CC - reticular formation of brainstem - thalamus
27
clonic and post ictal phase
results from massive activation of inhibitory neurons in brain
28
what simultaneously occurs durng colonic and post ictal phase?
autonomci overload
29
two ways determined between grand mal and secondary generalized
secondary generalized has - aura before hand - repetitive movements (blinking, twtching lip smacking) beforehand
30
JME is due to a
mutated GABA R
31
petit mal seizures generally originate from
upper brainstem
32
todd paralysis occurs if
motor cortex is involved
33
how do secondary generalized seizures spread
via corpus callosum and/or reticular formation
34
secondary generalized seizures can be
tonic tonic-clonic clonic
35
jacksonian march
upper extremity-->face-->trunk--> lower limb
36
foci in primary visual cortex results in
uniformed flashes, spots, and zig-zags of light
37
foci in visual association cortex
hallucinations such as floating balloons, stars, polygons
38
more anterior in visual association area (posterior temporal or parietal lobes)
more complex sensory hallucinations (people talking, etc)
39
seizure near uncus of rostral medial temporal lobe
hallucinations of smell and taste
40
why don't cortical seizures generalize
collateral inhibition present in normal brain to prevent excessive excitation
41
eplepsia partialis continua
less life threatening due to focal neuronal damage, but tendency to generalize into Major Motor Status Epilepticus, so important to terminate