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HEMATOLOGY 1 > ERYTHROCYTE > Flashcards

ERYTHROCYTE Flashcards

(58 cards)

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1
Q

WHAT IS THE NORMAL LIFE SPAN OF RBC?

A

120 DAYS

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2
Q

WHERE DOES THE ERYTHROPOIETIN PRODUCES?

A

KIDNEY

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3
Q

THIS STAIN USED TO ENUMERATE RETICULOCYTE

A

SUPRAVITAL STAIN

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4
Q

ONE OF THE BEST INDICATORS OF BONE MARROW FUNCTION

A

RETICULOCYTE COUNT

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5
Q

A YOUNG CELLS RELEASED FROM BONE MARRW AFTER OLDER RETICULOCYTES HAVE BEEN RELEASED. THIS IS A RESPONSE TO INCREASED NEED..

A

STRESS RETICULOCYTE

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6
Q

NORMAL CELL HAVE A CENTRAL PALLOR THAT IS ____

A

ONE THIRD

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7
Q

DECREASED CENTRAL PALLOR IS SEEN WITH

A

SPHEROCYTIC DISORDER INCLUDING THERMAL INJURY AND LIVER DISEASE.

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8
Q

CENTRAL PALLOR GREATER THAN THE NORMAL SIZE IS SEEN IN

A

MACROCYTIC ANEMIA

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9
Q

REFERENCE RANGE OF RBC IN WOMEN
MEN

A

FEMALES: 4.0-5.4
MALE: 4.6-6.0

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10
Q

ERYTHROPOIESIS IS REGULATED BY:

A

ERYTHROPOIETIN

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11
Q

WHAT ARE THE OTHER REGULATIONS IN RBH INCLUDES:

A

HYPOXIA DUE TO HIGH ALTITUDES, HEART OR LUNG DYSFUNCTION, ANEMIA
ANDROGENS AND HEMOLYTIC ANEMIA

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12
Q

WHAT ARE THE SUBSTANCES NEEDED FOR ERYTHROPOIESIS

A

IRON
AMIINO ACID
FOLIC ACID./ VIT. B12
OTHERS: ERYTHROPOIETIN , VIT B6, TRACE MINERALS

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13
Q

EVENLY SPACED ROUND PROJECTIONS , CENTRAL PALLOR ARE PRESENT

A

ECHINOCYTES INCLUDE BURR CELL AND CRENATED

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14
Q

UNEVENLY SPACED POINTED PROJECTIONS AND LACK OF CENTRAL PALLOR

A

ACANTHOCYTES

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15
Q

SHOWS A CENTRAL AREA OF HEMOGLOBIN SURROUNDED BY A COLORLESS RING AND A PERIPHERAL RING OF HEMOGLOBIN
CELLS AHVE A INCREASED SURFACE TO VOLUME RATIO

A

TARGET CELL

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16
Q

DISC SHAPED CELL WITH A SMALLER VOLUME THAN A NORMAL ERYTHROCYTE, CELLS HAVE A DECREASED SURFACE TO VOLUME RATIO

A

SPHREOCYTE

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17
Q

PEARED SHAPE WITH ONE BLUNT PROJECTION

A

TEARDROPS (DACROCYTE)

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18
Q

SHAPES VARY BUT SHOW THIN, ELONGATED, POINTED ENDS AND WILL APPEAR CRESCENT SHAPED USUALLY LACK OF CENTRAL PALLOR

A

SICKLE CELLS

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19
Q

INTERIOR PORTION OF CELL IS HOLLOW, RESEMBLING A HORN OR HELMET

A

HELMET CELLS

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20
Q

DAMAGED RBC, FRAGMENTS OF VARIOUS SIZES AND SHAPES ARE PRESENT OFTEN WITH POINTED PROJECTIONS

A

SCHISTOCYTES

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21
Q

CHARACTERIZEDBY AN ELONGATED OR SLIT-LIKE AREA OF CENTRAL PALLOR

A

STOMATOCYTE

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22
Q

CIGAR TO EGG SHAPED RBC

A

ELLIPTOCYTE

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23
Q

WHAT DISEASES CAN A ECHINOCYTES PRESENT?

A

LIVER DISEASE
UREMIA
HEPARIN THERAPY
PYRUVATE KINASE DEFICIENCY

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24
Q

WHAT DISEASES CAN A ACHANTOCYTE PRESENT?

Study These Flashcards
A

ALCOHOLIC LIVER DISEASE
POST SPLENECTOMY
ABETALIPOPROTEINEMIA

25
WHAT DISEASES CAN A TARGET CELL PRESENT?
LIVER DISEASE, HEMOGLOBINOPATHIES, THALASSEMIA, IDA,
26
WHAT DISEASES CAN A SPHEROCYTES PRESENT?
DAMAGED RBC: G6PD DEFICIENCY, HEREDITARY SPHEROCYTOSIS, IMMUNE HEMOLYTIC ANEMIA MICROSPHEROCYTES: SEVERE THERMAL INJURY
27
WHAT DISEASES CAN A TEARDROP CELLS PRESENT?
MEGALOBLASTIC ANEMIA THALASSEMIA EXTRAMEDULLARY HEMATOPOIESIS
28
WHAT DISEASES CAN A SICKLE CELL PRESENT?
HEMOGLBINOPATHIES SS, SC, SD
29
WHAT DISEASES CAN A HELMET CELLS PRESENT?
MICROANGIOPATHIC HEMOLYTIC ANEMIA
30
WHAT DISEASES CAN A SCHISTOCYTE PRESENT?
Microangiopathic HEMOLYTIC ANEMIA, G6PD DEFICIENCY, THERMAL INJURY, RENAL TRANSPLANT REJECTION.
31
WHAT DISEASES CAN A STOMATO CYTES PRESENT?
LIVER DISEASE, HEREDITARY STOMATOCYTOSIS OR AN ARTIFACT
32
WHAT DISEASES CAN A ELLIPTOCYTES PRESENT?
HEREDITARY ELLIPTOCYTOSIS, IDA, MEGALOBALSTIC ANEMIA, THALASSEMIA MAJOR.
33
THE NRBCS AR USUALLY APPEAR IN
ORTHOCHROMIC NORMOBLASTS
34
THIS RBC INCLUSIONS INDICATE BONE MARROW STIMULATION OR INCREASED ERYTHROPOIESIS
NUCLEATED RBC
35
SMALL, ROUND DNA FRAGMENT USUALLY ONE PER CELL, BUT CAN BE MULTIPLE STAIN DARK PURPLE TO BLACK IN WRGHT STAIN
HOWELL JOLLY BODIES
36
HOWELL - JOLLY BODIES IS SEEN
SICKLE CELL ANEMIA, BETA THALASSEMIA MJOR, OTHER SEVERE HEMOLYTIC ANEMIA, MEGALOBLASTIC ANEMIA, ALCOHOLISM POST SPLENECTOMY.
37
COARSE INCLUSION (RIBOSOMAL RNA REMNANTS)
BASOPHILIC STIPPLING
38
BASOPHILIC STIPPLING IS SEEN IN
THALASSEMIAS, MEGALOBLASTIC ANEMIA, SIDEROBLASTIC ANEMIA, LEAD POISONING, AND ALCOHOLISM
39
DARK STAINING IRON GRANULES USUALLY CLUMPED TOGETHER AT PERIPHERY OF THE CELL
PAPPENHEIMER BODIES
40
WHAT STAIN IS SED IN PAPPENHEIMER BODIES?
PERL’S PRUSSIAN BLUE STAIN
41
PAPPENHEIMER BODIES IS SEEN IN
SIDEROBLASTIC ANEMIA, HEMOGLOBINOPATHIES, THALASSEMIA MEGALOBLASTIC ANEMIA MYELODYSPLASTIC SYNDROME RARS
42
THIN, RED VIOLET. SINGLE TO MULTIPLE RINGLIKE STRUCTURES THAT MAY APPEAR IN LOOP OR FIGURE OF EIGHT SHAPES
CABOT RINGS
43
CABOT RINGS ARE SEEN IN
MEGALOBLASTIC ANEMIA, MYELODYSPLASTIC SYNDROME, LEAD POISONING
44
ROD SHAPE CRYSTAL
HEMOGLOBIN C
45
ONE TO TWO BLUNT, FINGERLIKE PROJECTIONS EXTENDING FROM THE CELL MEMBRANE. WASHINGTON MONUMENT
HEMOGLOBIN SC
46
INVISIBLE WITH WRIGHT STAIN REPRESENTS DENATURED HEMOGLOBIN
HEINZ BODIES
47
HEINZ BODIES IS SEEN IN
G6PD DEFICIENCY BETA-THALASSEMIA MAJOR HGB H DISEASE UNSTABLE HEMOGLOBINPATHIES DRUG INDUCED ANEMIAS
48
MCH AND MCHC IS DECREASED CENTRAL PALLOR IS GRATER THAN 1/3 OF THE DIAMETER
HYPOCHROMASIA
49
HYPOCHROMASIA IS SEEN IN
IDA, THALASSEMIA, ANEMIA OF CHRONIC DISEASE, SIDEROBLASTIC ANEMIA, MYELODYSPLATIC SYNDROME
50
VARIATION IN HGB CONTENT SHOWING A SLIGHT BLUE TIGER WHEN STAINED WITH WRIGHT STAIN; RESIDUAL RNA
POLYCHROMASIA
51
STACKING OF COIN PATTER OF RBC DUE TO
ABNORMAL OR INCREASED PLASMA PROTEINS
52
STACKING OF COIN
ROULEAUX
53
TRUE ROULEAX FORMATION IS SEEN IN
THIN AREA F THE PERIPHERAL SMEAR
54
AN ROULEAUX THAT CONSIDER ARTIFACT IS SEEN IN
THICKER AREA OF THE PERIPHERAL SMEAR
55
CHARACTERIZED BY CLUMPING OF RBC WITH NO PATTERN.
AGGLUTINATION
56
AGGLUTINATION OCCURS
RBC ARE COATED WITH IGM ANTIBODIES AND COMPLEMENT
57
AGGLUTINATION SEEN IN
COLD AUTOIMMUNE HEMOLYTIC ANEMIA
58
WHAT IS THE REMEDY FOR THE AGGLUTINATION
WARM BLOOD AT 37C TO CORRECT A FALSE LOW RBC AND HCT AND FALSE HIGH MCHC

HEMATOLOGY 1 (8 decks)

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