ESR [017]: Endocrine Aspects of Obesity Flashcards
(34 cards)
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The five risk factors of obesity ?
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• increased blood pressure (> 130/85 mmHg)
• high blood sugar levels (insulin resistance)
• excess fat around the waist
• high triglyceride levels
• low levels of good cholesterol (HDL)
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Mechanism of Inflammation in Obesity ?
And how does it present histologicaly ?
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Insulin resistance:
Due to inhibition of the insulin signaling pathway, either by:
-inflammatory cytokines, or
-phosphorylation >> inhibiting components of the insulin signaling pathway
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…..tissue expresses most of the components of RAS system.
Adipose
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Explain The renin–angiotensin system (RAS)
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Obesity is linked with alteration of…… secretion and an increased risk of incidence of some types of cancer.
adipokine
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How may Altered adipokine secretion lead to cancer ?
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