Hormonal Gene regulation: Nuclear receptors-006 Flashcards
(35 cards)
1
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their functions ?
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2
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What are Transcription factors ?
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3
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6
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Mechanism of work of Type I nuclear receptors ?
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8
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Explain
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9
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10
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11
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How does ligands of Type IV nuclear receptors bind ?
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12
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explain
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13
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14
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15
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3 types of Transcriptional activities of Nuclear receptors ?
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Explain the figure
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GR dysfunction Associated Diseases ؟
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ER-α dysfunction Associated Diseases ?
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Other ER-α dysfunction Associated Diseases ?
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AR dysfunction associated dsieases ?
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TRα dysfunction associated diseases ?
TRα dysfunction is assiciated with pituitary adenomas and thyroid cancer.
31
TRβ dysfunction associated diseases ?
TRβ dysfunction is assiciated with generalized resistance to thyroid hormone (RTH) in addition to Grave's disease, and psychological traits such as low intelligence.
32
RARα dysfunction associated diseases ?
RARα dysfunction is assiciated with a variety of types of cleft palate, as well as with schizophrenia and other psychiatric conditions
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RARβ dysfunction associated diseases ?
RARβ dysfunction has been shown to be associated with schizophrenia, autism, alcoholism, bipolar disorder and attention deficit hyperactivity disorder.
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RARγ dysfunction associated diseases ?
RARγ dysfunction has been shown to be associated with schizophrenia and other psychiatric conditions.
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VDR dysfunction associated diseases ?
