Ethanol tox

Question 1

Sources of ethanol

Answer 1

alcoholic beverages, perfumes, colonges, mouthwashes, hand sanitisers, detergents, methylated spirits, vanilla extract

Question 2

Lethal dose of ethanol in an adult if taken as a single ingestion

Answer 2

5-8g/kg
10ml/kg

Question 3

Lethal dose of ethanol in a child if taken as a single ingestion

Answer 3

3g/kg
4ml/kg

Question 4

How to calculate mass of ethanol (g)

Answer 4

vol ingested (L) x % amount of ethanol in the product consumed x 0.8 x 10

Question 5

When does serum ethanol concentration peak post ingestion

Answer 5

60-90min

Question 6

At what serum concentration does ethanol cause death

Answer 6

> 98mmol/L

Question 7

Clin F of mild ethanol intoxication

Answer 7

Disinhibtion, sociable, euphoria
Impaired judgement, impaired coordination, hypoglycemia

Question 8

Clin F of moderate ethanol intoxication

Answer 8

Slurred speech, impaired gait/ balance, vomits, tachycardia,, CNS depression/ confusion

Question 9

CLin F of severe ethanol intoxication

Answer 9

Coma, ataxia, difficulty sitting upright, hypoglycemia, seizures, pulmonary aspiration

Question 10

Clin F of life threatening ethanol intoxication

Answer 10

coma, refractory hypotension, metabolic acidosis, respiratory depression, cardiac arrest

Question 11

When are investigations undertaken for ethanol intoxication

Answer 11

Moderate to severe features or if in a child

Question 12

Ix - ethanol intox

Answer 12

Serum ETOH conc
BGL
UEC
Blood gas and lactate

Question 13

Indications for hemodialysis in ethanol intoxication

Answer 13

Hypotension requiring use of inotropes + ETOH conc of >98 mmol/L