Everything Session 8 (Screening) Flashcards

1
Q

What is the definition of screening?

A

Presumptive identification of unrecognised disease or defect via examination
If tests are positive further diagnostic tests done

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2
Q

What is the purpose of screening?

A

Prepare
Management
Plain in advance to reduce overall cost and burden

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3
Q

What are the 5 screening criteria areas?

A

-The condition
-The test
-The intervention
-The screening programme
-Implementation

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4
Q

What are the criteria for The Condition for Screening?

A

Must be an important health problem with known epidemiology, incidence, prevalence and history
All cost effective primary prevention has been implemented

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5
Q

What are the criteria for The Test for screening?

A

Test needs to be simple, safe, precise and valid
The cut off value is defined and agreed
There must be an agreed policy on further diagnostic investigation

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6
Q

What are the criterias for the screening programme of screening?

A

Needs to have proven effectiveness reducing mortality/morbidity
Evidence the screening programme is clinically, socially, and ethically acceptable
The benefits must outweigh the harm (over diagnosis, false positives)
The COST needs to be economically balanced

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7
Q

What are the criteria for implementation of screening?

A

All other management options have been considered
Needs adequate staffing and facilities for screening
Patients need to make their own informed choice

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8
Q

What are the 3 difficulties in evaluating screening programmes?

A

-lead time bias
-length time bias
-selection bias

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9
Q

What is lead time bias?

A

It is where early diagnosis appears to prolong survival however patients who are earlier diagnosed live the same time as someone who isn’t, they just live knowing they have the disease

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10
Q

What is length time bias?

A

Screening programmes are not good at picking up aggressive and sudden diseases
They are good at picking up slow growing things that may not cause an issue

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11
Q

Wha is selection bias?

A

When screening studies are skewed by healthy volunteers
Those who attend engulf screening are likely to attend other screening programmes and participate in other positive Health elated behaviours

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12
Q

Informed consent is required for all screening programmes? What does a lay person need in order to make and informed decision?

A

Benefits communicated
Harms and risks of the prevention communicated
Person has the capacity to understand and weigh up these benefits and risks

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13
Q

What are the 3 risks/types of error that come with screening?

A

False positives
False negatives
Over diagnosis

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14
Q

What is a false positive testing error?

A

Healthy individuals ho don’t have the disease are falsely referred for further investigation

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15
Q

What is a false negative testing error?

A

Unhealthy individuals who have the disease are told that they are healthy

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16
Q

What is over diagnosis?

A

When a correct true positive was given, however the result/feature that was detected may not actually develop into the disease

17
Q

What type of prevention is Screening?

A

Secondary prevention

18
Q

What are the 5 factors affecting screening uptake?

A

Acceptability of the test (non-invasive)
Awareness of benefits of screening
Convenience
Accessibility of information
Reminders and endorsements

19
Q

Why is their inequalities in the uptake of screening?

A

-Demographic factors
-Level of affluence
-Deprivation
-Ethnic diversity

20
Q

What are some UK screening programmes?

A

Cervical cancer
Diabetic eye screening
Bowel cancer screening
Breast cancer screening
Abdominal aortic aneurysm

21
Q

What are the 3 types of screening?

A

Population (everyone)
Targeted
Stratified

22
Q

What is the sensitivity of a screening test?

A

The proportion of the people with the disease who test positive
Also called the detection rate

23
Q

What is Specificity of the test?

A

The proportion of people without the disease who test negative

24
Q

What is the positive predictive value?

A

The probability that someone who tests positive has the disease (True positive)

25
Q

What is the negative predictive value?

A

The probability that someone who tests negative actually doesn’t have the disease (True negative)