Ex 2- Periodontium 1- Development Flashcards

(37 cards)

1
Q

What structures does the periodontium include?

A
cementum
PDL
bony socket
gingival facing tooth:
--junctional epithelium
--sulcular epithelium
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2
Q

______ is a calcified material that covers the root dentin

A

cementum

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3
Q

______ ______ is largely composed of collagen fibers which are embedded on one end into the cementum and on the other the bony socket housing the tooth

A

periodontal ligament

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4
Q

All of the structures of the periodontium serve s an attachment apparatus for the tooth except _______ ______

A

sulcular gingiva

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5
Q

Tooth root develops _______ the crown

A

after

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6
Q

_____ ______ ____ _____ (____) guides the growth of the root

A

Hertwig’s epithelial root sheath (HERS)

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7
Q

The initiation of root dentinogenesis slightly precedes _______ development

A

periodontal

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8
Q

The inductive signal from HERS for odontoblast differentation is _________ and/or _______

A

TGF-B and/or laminin5

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9
Q

Once dentin in the root begins to be laid down, _____ separates from root dentin. Cells migrate to root dentin to become _________, to site of future tooth socket to become ______ and to the future PDL to become ________

A

HERS
cementoblasts
osteoblasts
fibroblasts

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10
Q

______ & ________ secrete their organic matrix composed primarily of type I collagen then the ______ _______ secrete their own organic collagen matrix

A

Cementoblasts & osteoblasts

PDL fibroblasts

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11
Q

The organic matrices of cementum and bone are secreted before _________ begins

A

mineralization

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12
Q

As the PDL fibers are secreted they intermingle in _________ matrices then become entrapped in those matrices during ______ in the cementum on one side and the alveolar bone on the other

A

unmineralized

mineralization

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13
Q

All of periodontal development, including PDL development, is occurring as the tooth is ______

A

erupting

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14
Q

As the tooth is erupting, _______ fibers of the PDL get added apically, the ______ of PDL fibers also change

A

collagen

orientation

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15
Q

Collagen fiber bundle starts in an ______ orientation with ends embedded in the cementum more ______ positioned. Then to a more _________ position, then _____ again with the cementum more ______

A
oblique 
apically
horizontal
oblique
coronal
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16
Q

The periodontium growth proceeds from the _____ to the ______ ______ occurring simultaneously with eruption. 2 processes are coordinated and slow

A

CEJ

root apex

17
Q

_______ cementum is the first type of cementum formed, mainly acellular, located on coronal ____ of root

18
Q

________ cementum is fromed after @ least ____ of the root is formed to the time the tooth emerges in the oral cavity, mainly cellular, located on apical ____of root

A

secondary
1/2
2/3

19
Q

_________ cementum is most important in serving an attachment function

20
Q

The 2 types of cementum overlap in the ______third of the root, with _____ cementum overlying ______ cementum

A

middle
secondary
primary

21
Q

Along the advancing root edge, there is the continuous stretch of predentin extending btw the future _____ and the _____

22
Q

A little coronal to the tip of the developing root, the root dentin starts to _______ creating _____, separate ______parts of dentin: the ______ adjacent to the pulp and another region at the future _____

A
mineralize
two
unmineralized 
predentin
DCJ
23
Q

_____ ______ a dense group of collagen fibers oriented at _______ angles to the DCJ

A

fiber fringe

right

24
Q

The fiber fringe extends into the _______ ______ ____ . Upon mineralization the fiber fringe is embedded within the mineralized dentin matrix

A

unmineralized dentin matrix

25
The firm attachment between the cementum and _____ is a consequence of the ______ ______ of these 2 tissues _______ prior to mineralization
dentin collagen fibers intermingling
26
As cementoblasts secrete primary cementum the cementoblasts _____ become entrpped in the ECM they are making (acellular); rather they _____toward the location of the future PDL (cellular)
don't | retreat
27
The adult PDL contains remnants of the Hertwig's epithelial root sheath called _____ ______ ___ ______
epithelial rests of Mallasez
28
What are the similarities between cementogenesis of primary and secondary cementum?
DCJ formed in same way- collagen fibers of cementum (fiber fringe) + dentin intermingle prior to mineralization
29
What are the differences between cementogenesis of primary and secondary cementum?
cementoblasts become trapped in secondary cementum matrix (called cementocytes) bc deposited more rapidly (cellular secondary cementum)
30
Sulcular epithelium arises from embryonic ____ _______ and junctional epithelium arises from _______ ______ ____
oral epithelium | reduced enamel epithelium
31
All cells of the connective tissue components of the periodontium (PDL, bony tooth socket, cementum) arise from precursor cells of ______ ______
dental follicle
32
_________ may arise from the follice or from HERS cells that undergo epithelial-mesnchymal transformation
cementoblasts
33
Cementoblasts may derive from both ______ AND _____ ______
HERS | dental follicle
34
______ are secreted growth factors (signaling molecule) belonging to TGF-B superfamily
BMPs (bone morphogenic proteins)
35
______ is transcription factor implicated in cementoblast differentiation
RunX
36
______ _____and ____ are both secreted from cementoblasts about the same time as the initial collagen matrix: role in mineralization
Bone sialoprotein | osteopontin
37
_______ _____ may play a role in cementoblast adhesion to the root dentin surface and in triggering the mineralization of cementum but they also bind to _______
``` bone sialoprotein (BSP) collagen ```