EXAM 1 Cell and Molec Flashcards

(56 cards)

1
Q

helps DNA condense into chromatin

A

histones

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2
Q

mRNA is synthesized here

A

nucleus

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3
Q

these allow organ formation and cell to cell interaction

A

intercellular junctions

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4
Q

highest strength of intercellular junctions

A

tight junctions

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5
Q

intercellular junction that helps adhere to basil lamina

A

hemidesmosome

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6
Q

intercellular junctions that allow small molecule passage

A

gap junctions

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7
Q

in cell membrane, center of bilayer is _____.

A

hydrophobic

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8
Q

proteins that penetrate into cell membrane

A

integral

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9
Q

hydrophilic proteins associated with outside of membrane

A

peripheral

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10
Q

microtubules and microfilaments are what type of proteins?

A

cytoskeletal proteins

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11
Q

functions of cytoskeletal proteins

A

maintain shape, allow movement, facilitate polarity, cytotoxic transport

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12
Q

examples of muscular motors

A

actin, myosin, dyenin, kinesin

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13
Q

vesicles that contain large amounts of lytic enzymes

A

lysosomes

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14
Q

lysosomes role

A

degrade molecules

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15
Q

site of most ATP production

A

mitochondria

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16
Q

B-oxidation and oxidative phosphorylation occur here

A

mitochondria

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17
Q

when nucleotides are degraded what is produced?

A

URIC acid

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18
Q

what causes gout?

A

accumulation of uric acid

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19
Q

in chemotherapy why do patients uric acid levels climb?

A

a lot of cell death occurring

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20
Q

formed from a SINGLE chain of nucleotides

A

RNA

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21
Q

secreted proteins are made on the ________

A

endoplasmic reticulum

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22
Q

coding parts of DNA are called____.

A

EXONS

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23
Q

noncoding parts of DNA are called ____.

24
Q

Deamination yields _____.

25
what starts Urea cycle?
NH4
26
lab tests that are important functions of liver damage
ALT, AST
27
When the Krebs cycle is unable to process acetyl-coA, what is produced?
KETONES
28
If there are ketones in urine, pt is using a high level of ____ for energy.
fat
29
pathway that uses amino acids and turns it back into glucose
gluconeogenesis
30
Energy source in fat
long carbon chains
31
In B-oxidation, for each acetyl- coA, we can obtain ___ ATP
18
32
process where glycogen can be turned back into glucose
glycogenolysis
33
pathway that starts with pyruvate and will end up with 36 ATP per glucose
Krebs cycle
34
does glycolysis require oxygen?
no
35
pathway where we get 2 ATP per glucose molecule
glycolosis
36
the ultimate source of energy for biological reactions are compounds with _____.
high-energy phosphate bonds
37
what is normal plasma osmolality?
285-295 mOsm/kg
38
osmolality is calculated by what three compounds in blood?
sodium, glucose, blood-urea nitrogen
39
causes cells to swell
hypotonic solution
40
solution that causes cell to shrink
hypertonic
41
primary cation in ECF
sodium
42
primary anion in ECF
chloride
43
primary cation in ICF
potassium
44
how do capillaries separate blood from interstitial fluid?
basement membranes
45
blood and interstitial fluid make up the _____.
extracellular fluid
46
makes up 2/3 of total body fluid
intracellular fluid
47
% of blood plasma in human fluid
5%
48
ECF and ICF make up what percent of body weight?
55-65%
49
normal somatic cells are _____.
diploid
50
phase in mitosis where initial cell growth begins
G1
51
mitosis phase that most cells are in
G0
52
dna synthesis occurs to form tetraploid cells in this phase of mitosis
S phase
53
mitosis phase that has continued cell growth before division
G2
54
cell division phase of mitosis
M Phase
55
cell proliferation in germ cells is done by ____.
meiosis
56
in meiosis, chromatids separate to form how many haploid cells?
4