Exam 1 Review: Flashcards

1
Q

A dominant allele causes freckles. A man has freckles but one of his parents does not have freckles. What is the man’s genotype?

A) Homologous
B) Heterozygous
C) Homozygous dominant
D) Heterologous
E) Homozygous recessive

A

B) Heterozygous

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2
Q

Cells that carry two sets of genetic information are:

A) Haploid
B) Diploid
C) Polyploid
D) Homologous
E) Paired

A

B) Diploid

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3
Q

The ability to roll the tongue is caused by a dominant allele. A woman is a “roller”, but one of her parents is not. What is the woman’s genotype?

A) Either homozygous recessive or homozygous dominant
B) It cannot be determined from this information
C) Heterozygous
D) Homozygous recessive
E) Homozygous dominant

A

C) Heterozygous

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4
Q

About 70% of Americans perceive a bitter taste from the chemical phenylthiocarbamide (PTC). The ability to taste this chemical results from a dominant allele (T) and not being able to taste PTC is the result of having two recessive alleles (t). Albinism is also a single locus trait with normal pigment being dominant (A) and the lack of pigment being recessive (a). A normally pigmented woman who cannot taste PTC has a father who is an albino taster. She marries a normally pigmented man, who is homozygous at the albinism locus, and who is a taster but who has a mother that does not taste PTC> Which of the following choices list ONLY possible genotypes of their children (all listed are possible)?

a) A/A; T/T — A/a; T/T — a/a’ T/T
b) A/A; T/t — A/a;T/t — a/a;T/t
c) A/A; t/t — A/a’ t/t — a/a; t/t
d) A/A; T/t — A/a; T/t — A/a; t/t

A

d) A/A; T/t — A/a; T/t — A/a; t/t

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5
Q

A form of a gene that has slightly different sequence than other forms of the same gene but encodes the same type of an RNA or protein is called a(n):

a) homologous chromosomes
b) homozygotes
c) allele
d) heterozygote
e) locus

A

c) allele

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6
Q

If a human trait is never passed from father to son, it is likely that this trait is:

a) dominant
b) recessive
c) autosomal
d) Y-linked
e) X-linked

A

e) X-linked

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7
Q

Hair color is determined in labrador retrivers by alleles at the B and E loci. A dominant allele B encodes black pigment, whereas a recessive allele b encodes brown pigment. Alleles at a second locus affect the deposition of the pigment in the shaft of the hair; dominant allele E allows dark pigment (black or brown) to be deposited, whereas recessive allele e prevents the deposition of dark pigment, causing the hair to be yellow. A black female labrador retriever was mated with a yellow male. Half of the puppies were black, and half were yellow. If the genotype of the black female parents was B/b;E/e, then what was the genotype of the other parent?

a) b/b;e/e
b) B/B;E/E
c) B/b;e/e
d) B/B;e/e
e) b/b;e/e

A

d) B/B;e/e

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8
Q

Whilde doing filedwork in Madagascar, you discover a new dragonfly species that has either red (R) o clear (r) wings. Inital crosses indicate that R is dominant to r. You preform three crosses using 3 different sets of red-winged parents with unknown genotypes and observe the following data:

Cross 1: 72 red-winged, 24-clear-winged
Cross 2: 12 red-winged
Cross 3: 96 red-winged

Which cross(es) is/are likely to have at least one parent with the genotype R/R?

a) cross 3
b) crosses 2 and 3
c) cross 2
d) crosses 1 and 2
e) cross 1

A

b) crosses 2 and 3

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9
Q

Is it better to have a large sample size in genetic crosses?

a) Yes, larger sample sizes mean there are more degrees of freedom
b) No, larger sizes lead to more errors in counting
c) No, larger sample sizes results in greater deviation from expected ratios
d) Yes, larger sample sizes can produce phenotypic ratios closer to the expected ratios

A

d) Yes, larger sample sizes can produce phenotypic ratios closer to the expected ratios

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10
Q

In Drosophila melanogaster, the level of expression of genes on the X chromosome in males is double. What phenomenon is this an example of?

a) paternal mitochondrial leakage
b) dosage compensation
c) extranuclear inheritance
d) genomic imprinting

A

b) dosage compensation

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11
Q

You discoer a new mutation in Drosophilia that causes an abnormal wing shape. When a male fly with this mutation is crossed to a homozygous normal female, the F1 are all wild-type phenotypically. The F2 flies consist of 1/2 phenotypically normal females, 1/4 phenotypically normal males, and 1/4 males with abnormal wings. What is the MOST likely explanation for the new mutant allele?

a) It is x-linked and recessive
b) It is y-linked
c) It is autosomal and dominant
d) Is is autosomal and recessive
e) It is x-linked and dominant

A

a) It is x-linked and recessive

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12
Q

A certain type of congenital (inherited) deafness in humans is caused by a rare autosomal dominant gene. A deaf man and a deaf woman with this form of deafness marry and have lots of children. Would you expect all of the children to be deaf, assuming Mendelian phenotype ratios?

A

No

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13
Q

In dogs, black coat color (B) is dominant over brown (b), and solid coat color (S) is dominant over white spotted coat (s). A cross between a black, solid female and a black, solid male produces only puppies with black, solid coats. This same female was then mated with a brown, spotted male. Half of the offspring from this cross were black and solid, and half of the offspring were black and spotted. What is the genotype of the brown spotted male?

a) b/b;s/s
b) B/B; S/s
c) B/B;S/s
d) B/B; S/S
e) B/b;S/S

A

a) b/b;s/s

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14
Q

The ability to curl one’s tongue into a U-shape is a genetic trait. Curlers always have at least one curler parent but noncurlers can have one or both parents who are curlers. Using C and c to symbolize the alleles that control this trait, what is the genotype of a non curler?

a) c/c
b) C/c
c) C/C or C/c
d) C/C

A

a) c/c

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15
Q

An allele for purple fur color in muppets (P) is dominant to an allele for white fur color (p). Heterozygotes for purple exhibit 50% penetrance. The following cross is carried out: P/p x p/p. What proportion of the progeny will be purple?

a) 1
b) 0.25
c) 0
d) 0.5
e) 0.125

A

b) 0.25

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16
Q

A measurable or observable trait or characteristic is called a:

a) phenotype
b) genotype
c) small interfering RNA
d) single-nucleotide polymorphism
e) gene bank

A

a) phenotype

17
Q

A new muntjac species that you are studying has 9 different chromosomes. Like all mammals, the muntjac is diploid. How many chromosomes would you expect to to see in a normal somatic (non-gamete) cell from this organism?

a) 18
b) 72
c) 36
d) 8
e) 9

A

a) 18

18
Q

Which of the following are NOT prokaryotes?

a) viruses
b) ancient bacteria
c) eubacteria
d) archaea

A

a) viruses

19
Q

In horses, the black coat color is due to a dominant allele B, and the chestnut coat color is due to a recessive allele b. The trotting gait is due to a dominant allele T, and the pacing gait to the recessive allele t. What gametes will be produced by a homozygous black pacer?

a) 50% B/b; T/t and 50% B/B; T/t
b) 50% B/B and 50% t/t
c) All B/B
d) All t/t
e) All B;t

A

e) All B;t

20
Q

The ability to roll up your tongue on the sides (T, tongue rolling) is dominants to the inability to roll your tongue (t). A woman who can roll her tongue has a child with a man who cannot roll his tongue. The child has his father’s phenotype. What is the mother’s genotype?

a. T/T
b. t/t
c. T/N
d. T/t
e. N/T

A

d. T/t

21
Q

Which type of dominance occurs when the heterozygote has the same phenotype as one of the homozygotes?

a. Complete dominance
b. Partial dominance
c. Codominance
d. Incomplete dominance
e. Overdominance

A

a. Complete dominance

22
Q

You are studying a gene that controls ossicone (horn) length in giraffes. The wild-type long-ossicone allele (L) is dominant to the mutant short-ossicone (l) allele. However, the L allele is only 60% penetrant. You cross two heterozygous giraffes. What proportion of offspring would you expect to exhibit the long-ossicone phenotype? Assume the penetrance of L applies equally to both homozygotes and heterozygotes.

a. 0.75
0.40
0.60
0.55
0.45

A

0.45

23
Q

An example of a phenotype is:

a. White eyes in Drosophila
b. Autosomal recessive
c. A/a
d. R/r; Y/y

A

a. White eyes in Drosophila

24
Q

Which of the following choices describes how information is normally transferred between biological molecules (aka the central dogma)

a. DNA&raquo_space; RNA&raquo_space; Protein
b. RNA&raquo_space; DNA&raquo_space; Protein
c. Protein&raquo_space; DNA&raquo_space; RNA
d. DNA&raquo_space; Protein&raquo_space; RNA

A

a. DNA&raquo_space; RNA&raquo_space; Protein

25
Q

The cells of a mature pea plant have 14 chromosomes. How many chromosomes does a nucleus in the pea endosperm contain?

a. 31/2
b. 30
c. 7
d. 21
e. 14

A

d. 21

26
Q

A mother with blood type A has a child with blood type A. Give all possible blood types for the father of this child.

a. A,B,O
b. B, AB
c. O
d. A,B,AB,O
e. A,AB

A

d. A,B,AB,O

27
Q

A Barr body is a(n)

a. Inactivated X chromosome, visible in the nucleus of a cell that is from a female mammal with normal chromosomes
b. Extra Y chromosome in a cell that is the result of nondisjunction
c. Extra X chromosome in a cell that is the result of nondisjunction
d. Patch of cells that has a phenotype different from surrounding cells because of variable X inactivation
e. Gene on the X chromosome that is responsible for female development

A

a. Inactivated X chromosome, visible in the nucleus of a cell that is from a female mammal with normal chromosomes

28
Q

Meiosis results in diploid cells.

a. True
b. False

A

b. False

29
Q

The yellow phenotype in mice has an unusual form of inheritance. Crossing two yellow mice results in 2/3 yellow offspring and 1/3 nonyellow offspring. What percentage of offspring would you expect to be nonyellow if you crossed two nonyellow mice?

a. 33%
b. 75%
c. 66%
d. 25%
e. 100%

A

e. 100%

30
Q

On average, what fraction of the genome is shared between full siblings? (ignore sex chromosomes for the purpose of this question)

a. 2/3
b. 1/8
c. 1/4
d. 3/4
e. 1/2

A

e. 1/2

31
Q

What are the structures in a cell that group genes together, are composed of chromatin (DNA and protein), and become visible under a light microscope during mitosis?

a. centromeres
b. chromosomes
c. nucleic acids
d. centrioles

A

b. chromosomes

32
Q

A researcher working on zebrafish is interested in the genetics of eye development. She isolates a series of mutant fish that all show a failure of retina development. She then breeds them, determines that the mutations are recessive, and develops pure-breeding strains from each original mutant. What would be a logical next step in her study of these mutations?

a. To perform a complementation test by crossing the mutant strains with wild type strains
b. To determine if the mutations are haplosufficient
c. To determine if any of the mutations are lethal
d. To determine if the mutations are dominant negative
e. To perform a complementation test by crossing the mutant strains with one another

A

e. To perform a complementation test by crossing the mutant strains with one another

33
Q

In the diploid cells of an organism, there can be _____ different allele(s) of a given single copy nuclear gene

a. Only one
b. One or two
c. Three
d. One, two, three, or four
e. Many

A

b. One or two