Exam 2 - VTE, DVT, PE Flashcards
(58 cards)
a blood clot due to endothelial injury, venous stasis, or hypercoagulability
venos thromboembolism
VTEs can be formed by…
collections of fat, air, cancer cells, or blood
____ is the most common blood clot
deep vein thrombosis
the two main complications that DVT can cause are…
disrupt perfusion, lead to PE
what is Virchow’s Triad?
(1) reduced blood flow
(2) blood vessel injury
(3) increased coagulability
name at least 3 causes of reduced blood flow
(1) A Fib
(2) immobility
(3) venous insufficiency
(4) bedrest
(5) prolonged sitting
name at least 3 causes of blood vessel (endothelial) injury
(1) trauma
(2) HTN
(3) surgery
name at least 3 causes of increased coagulability
(1) sepsis
(2) coagulation disorders
(3) increased viscosity r/t hypovolemia
s/s of DVT
(1) calf or groin tenderness and pain
(2) sudden onset of unilateral swelling of the leg
(3) Pos Homan sign (unreliable)
(4) skin red and warm, tight to touch
pain on the dorsiflexion of the foot is ___
Pos Homan sign
what tests are used to diagnose DVT?
(1) venous duplex ultrasound
(2) doppler flow study
(3) D-dimer test
positive D-dimer test is
> 250 ng/mL
negative D-dimer test is
<250 ng/mL
what are the main goals of DVT management?
(1) avoid increased size of thrombus
(2) avoid emboli
(3) prevent complications and injury
what are the 4 main medications for DVT?
(1) unfractionated heparin
(2) low molecular weight heparin (LMWH)
(3) warfarin
(4) DOACs
____ is the initial treatment for DVT
unfractionated heparin infusion
____ is a high-risk med that needs 2 nurse checks
heparin
what is the typical dose for unfractionated heparin?
(1) 5000 U/bolus
(2) 20-40,000 U/24 hours in 1L NS
LMWH route
SQ
why do we start warfarin while still on Heparin?
to bridge the heparin and then switch over to Warfarin - warfarin takes a few days to kick in
warfarin takes ____ days to reach therapeutic range
3-4
what is the initial dose of warfarin?
2-5 mg/daily
what is the maintenance dose of warfarin?
2-10 mg/daily
___ and ___ are examples of oral anticoagulants (DOACs)
apixaban; rivaroxaban