Exam 3 - Summary Set Flashcards
the normal physiologic response to disease-causing microorganisms and toxic substances
immunity
___ and ___ are the two types of immunity
innate, adaptive
____ is present at birth and non-antigen specific
innate immune system
what are 3 reasons that older adults are at higher risk of immune issues?
(1) reduced response to pathogens
(2) increase in autoimmune diseases
(3) impaired inflammation with comorbidities
type I immune responses are ____ reactions
allergic
tissue-specific or cytotoxic reactions are
type II immune responses
Serum sickness and Lupus are examples of ___ immune responses
type III
cell-mediated or delayed hypersensitivity is which immune response?
type IV
virus that affects the immune system and weakens it
HIV
which cells are impacted in HIV?
CD4+ T-helper cells and memory cells
name at least 4 risk factors / causes for HIV contraction
(1) direct contact with bodily fluids
(2) unprotected sexual activities
(3) sharing needles
(4) blood transfusion
(5) breast milk
(6) birth canal
the 3 phases of HIV are:
(1) phase I acute infection
(2) latent phase
(3) AIDS
s/s of acute HIV infection
(1) fever
(2) sore throat
(3) rash
(4) night sweats
(5) chills
(6) headache
(7) muscle aches
the diagnostic criteria for AIDS is
CD4+ count <200
at the beginning of HIV, we see a sharp increase in ____ and a sharp decrease in _____
HIV RNA virus; CD4+ T-cell count
the latent phase can last ___
1-11 years
why is it important to get re-tested for HIV?
because during the window period, there is a higher risk for false-negative test results
3 supportive diagnostics that indicate progression of HIV include:
(1) lymphocyte count
(2) CD4+ count
(3) viral load testing
treatment for HIV is ____
lifelong antiretroviral therapy (ART)
what is the key to HIV medication therapy?
combination of a med to decrease viral load and a med to support the immune system
The purpose of ART is to ___
prevent HIV from replicating AKA to decrease viral load
name at least 3 adverse effects of ART
(1) weight loss
(2) fatigue
(3) diarrhea
(4) mood changes
(5) high cholesterol
(6) N/V
(7) rash
what are the 5 outcomes / goals for HIV?
(1) prevent progression of HIV
(2) prevent transmission
(3) prevent opportunistic infections
(4) prevent complications r/t ART
(5) coordinate care
extensive, irreversible scarring of the liver from inflammation
cirrhosis