Exam 3 Flashcards

1
Q

The human body typically begins to be colonized by its normal flora….

A

during and immediately after birth.

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2
Q

Virulence factors include all the following

A
  • capsules
  • exoenzymes
  • endotoxins
  • exotoxins
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3
Q

STORCH is an acronym that represents…..?

syphilis, toxoplasmosis, other diseases, rubella, cytomegalovirus,herpes

A

infections of the fetus and neonate.

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4
Q

Microbial hyaluronidase, coagulase, and streptokinase are examples of?

A

exoenzymes

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5
Q

what are exotoxins?

A

lipopolysaccharides

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6
Q

what organ do the enterotoxins target?

A

intestines

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7
Q

what are the processes of infectious disease?

P1) IP, P2) PS, P3) PI, P4) CP

A

phase 1) incubation period
phase 2) prodromal stage
phase 3) period of invasion
phase 4) convalescent period

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8
Q

what is incubation period

phase 1

A

intital contact until apprerance of first syptoms, it is multiplying but not enough for damage
several hours —–> several days

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9
Q

what is prodromal period?

phase 2

A

vague feelings of discomfort but no complaints

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10
Q

what is period of invasion?

phase 3

A

multiplies at high levels and has more specific signs and syptoms

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11
Q

what is convalescent period?

phase 4

A

the immune system begins to respond to infection and syptoms decline

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12
Q

The stage of an infectious disease when specific signs and symptoms are seen at peak activity is called the?

A

period of invasion

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13
Q

The time from when pathogen first enters the body and begins to multiply, until symptoms first appear is the?

A

incubation period

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14
Q

The initial, brief period of early, general symptoms such as fatigue and muscle aches is the

A

prodromal stage

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15
Q

what is the subjective evidence of disease sensed by the patient called?

A

symptoms

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16
Q

what is the objective, measurable evidence of disease evaluated by an observer called?

A

signs

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17
Q

what is a disease that has a steady frequency over time in a population called?

A

endemic

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18
Q

what is the primary, natural habitat of a pathogen where it persists called?

A

reservoir

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19
Q

what is an animal that transmits a pathogen from one host to another called?

A

vector

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20
Q

what is an inanimate object that harbors and transmits a pathogen called?

A

fomite

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21
Q

what is resident flora?

A

microbes that exist in mutual association w/ humans

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22
Q

what is transient flora?

A

microbes that cause infection sites that harbour normal residents

penis, mouth, colon, eye lids, lashes etc.

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23
Q

where are areas in the body that are sterile?

A
  • uterus
  • internal eye
  • brain and spinal cord
  • liver
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24
Q

Adhesive pili, exotoxins, and capsules are all examples of

A

virulence factors

25
where are resident microbiota found? | s, m, li, np
- skin - mouth - nasal passages - large instestines
26
Someone who inconspicuously harbors a pathogen and spreads it to others is called a?
carrier
27
what are the diffrent portals of entry? | EX, EN
- exogenus - endogenus
28
what are exogenus agents?
orginate from sources outside the body
29
what is a endogenus agents?
normal flora
30
what are the specfic portals of entry? | s, R, GI, UG
skin, respiratory, gastrointestinal, urogenital
31
what are the two bacterial toxins?
- endotoxins - exotoxins
32
what is an endotoxin?
a toxin composed of part of the outer membrane that have gram neg cell walls
33
what are the syptoms of endotoxin?
fever, aches, shock
34
what is exotoxins?
secreted by living bacterial cells and disrupts the membrane
35
what is toxemia?
toxins spread through the blood - tetanus - diptheria
36
rabbits and rodents are resvoirs for what agent?
tularemia
37
what are the characteristics of pertuisis
whooping sounds
38
what is tyhe characteristics of enterobacciae
gluclose fermination
39
Which disease involves transmission by aerosolized water from whirlpool spas, air conditioners, cooling towers, and supermarket vegetable misters?
Legionellosis
40
what are the characteristics of E.coli infections?
- transmitted by fecal contaminated soil or water - UTI from normal flroa strains - involve enterotoxin in traveler's diarrhea. - cuases inflammatory disease
41
is somonella motile
yes
42
what are coliforms that cause opportunistic and nosocomial infections
- enterobacter - citrobacter - klebsiella - serratia
43
what are charaxcteristics of shigella
- non motile - realease endotoxins - enterobacciae genus - produce enterotoxin
44
how is Yersinia pestis transmitted?
flea vector
45
what is the gram-negative bacillus associated with abscesses from dog and cat bites or scratches?
Pasteurella multocida.
46
Up to 70% of travel-associated gastrointestinal diseases are caused by
enterotoxigenic strains of E. coli.
47
hich bacteria could be responsible for hemolytic uremic syndrome (HUS)?
E. coli 0157:H7
48
Whooping cough is transmitted via respiratory droplets. The __________ stage lasts 1–2 weeks, while the __________ stage is characterized by severe coughing.
catarrhal; paroxysmal
49
E. coli 0157:H7 characteristics include all the following, except
it only causes occupational illness in people who work with animals.
50
Which of the following is an agent of the sexually transmitted disease chancroid?
Haemophilus ducreyi
51
The buildup of mucus and blockage of airways in pertussis is due to
toxins that destroy the ciliated cells of the respiratory tract.
52
Production of enterotoxin is a characteristic of
Clostridium difficile.
53
Which organism can infect deeper wound sites and produce exotoxins, enzymes, and gas that cause tissue and muscle necrosis?
Clostridium perfringens
54
All of the following pertain to Listeria monocytogenes, except
production of endospores
55
Formation of a pseudomembrane in the back of the throat is seen in
diptheria
56
he major virulence factor of Corynebacterium diphtheriae that causes serious systemic effects is
its exotoxin.
57
What is the usual cause of pseudomembranous colitis?
Therapy with broad-spectrum antibiotics leading to superinfection by C. difficile
58
duction of a neurotoxin that prevents acetylcholine release from motor neurons at neuromuscular junctions is a characteristic of
Clostridium botulinum.
59
All of the following pertain to Clostridium difficile infection, except
it is due to ingestion of contaminated, improperly stored, cooked meats and gravies.