Exam 3 Flashcards

(90 cards)

1
Q

What is essential in TB medication administration, regardless of how the patient feels?

A

encourage completion of full course of meds to avoid multi-drug resistant TB, as well as revival of bacteria

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2
Q

What is DOT? Why is it used?

A

DOT: Directly observed therapy (watch pt take meds); it decreases resistance and improves cure rates

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3
Q

What is INH?

A

Isoniazid, an antitubercular drug

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4
Q

A patient receiving INH (isoniazid) for tuberculosis reports anorexia, malaise, fatigue, jaundice, and nausea. What might these indicate?

A

hepatitis

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5
Q

What are the most common adverse effects associated with the use of INH?

A

hepatitis and peripheral neuropathy

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6
Q

Your patient is taking RIPE (Rifampin, Isoniazid, pyrazinamide, ethambutol) for active TB. He comes in today & says “My contact lenses have turned red.” Which med caused it?

A

rifampin

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7
Q

What can be taken with INH (Isoniazid) to prevent peripheral neuropathy?

A

B6 (pyridoxine)

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8
Q

A 32 yo is taking RIPE. In addition to LFT, what else should be done for this patient? Why?

A

Ophthalmology exam
Patients receiving ethambutol should have baseline and periodic eye exams because of the drug’s risk of inducing optic neuritis.

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9
Q

Your patient has been prescribed RIPE. He protests to taking so many meds. What would be the best action for the nurse to take?

A

Explain the rationale for multi-drug therapy.

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10
Q

Patient education about INH should include limiting the intake of what examples of foods?

A

fish, avocados, and chocolate
Avocados and chocolate are high in tyramine and may cause hypertension. Tuna fish is high in histamine and may cause headache, palpitations, hypotension, or other reactions.

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11
Q

What action should be taken to minimize the adverse effects from INH (isoniazid), the nurse should monitor?

A

AST and ALT levels
these are liver enzymes and indicate liver functioning. Because hepatitis and other liver problems frequently are
adverse effects of INH, these enzymes should be monitored closely

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12
Q

What is amphotericin B used in the care of patients for?

A

a serious systemic mycotic disease; fungal infection

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13
Q

What do patients receiving amphotericin B have the greatest risk for the development of?

A

nephrotoxicity

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14
Q

Nystatin, an antifungal drug nearly identical to amphotericin B, is indicated for the treatment of what?

A

oral, cutaneous, mucocutaneous, or vaginal candidiasis

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15
Q

Before initiation of amphotericin B therapy, what patient teaching should you do?

A

“Many pts have a reaction to this med. I will premedicate you to diminish the risk.

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16
Q

You are to admin the 1st dose of amphotericin B for a systemic fungal infection. Before beginning the infusion, you should

A

administer an antipyretic, such as acetaminophen, assess vitals, and administer test dose

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17
Q

Your patient has had several ABX and now has oral thrush. How should you help her take it?

A

have the patient swish the suspension in her mouth before swallowing it

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18
Q

What is expected to occur with body fluids of those taking rifampin?

A

orange color

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19
Q

What is common among all antitubercular medications (Rifampin, Isoniazid, pyrazinamide, ethambutol)?

A

hepatotoxicity, require LFTs (liver function tests), contraindicated in liver disease, and should avoid alcohol

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20
Q

what refers to an antibiotic that affects many microorganisms?

A

broad spectrum

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21
Q

What labs should be taken prior to administering antibiotics?

A

culture and sensitivity

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22
Q

How much fluid intake should patients on sulfonamides maintain? Why?

A

1.5 L/day to prevent crystalluria

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23
Q

What syndrome can occur if vancomycin is infused too rapidly?

A

Red man Syndrome

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24
Q

What are high risk effects that may occur with vancomycin?

A

ototoxicity and nephrotoxicity

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25
What is an adverse effect of tetracyclines?
photosensitivity
26
What is a primary concern of penicillin?
allergic reactions
27
What is the black box warning for lincosamides?
severe possible fatal colitis
28
What effects may occur with fluoroquinolones (ciprofloxacin)?
achilles tendon rupture, arthropathy, superinfection, crystalluria, and hypersensitivity reactions
29
What kind of drugs are macrolides?
antibacterials
30
Why should those on cephalosporins avoid alcohol?
disulfiram-like-reaction
31
What should people allergic to penicillin wear?
medical alert ID
32
What drug may be used to treat UTIs that causes brown urine color?
nitrofurantoin
33
What is the prototype drug for cephalosporins?
cefazolin
34
What is bacteria present in the blood known as?
bacteremia
35
What is fluconazole (a triazole-broad spectrum fungistatic agent) often used to treat?
vaginal yeast infections
36
What may occur with urine while on -azole medications (broad spectrum fungistatic agents)?
dark colored
37
Acyclovir is an anti-viral medication used to treat?
chickenpox, shingles, herpes
38
What is an often irreversible adverse effect of ciprofloxacin?
arthropathy
39
What pregnancy category is isotretinoin?
Category X
40
What TB medication causes orange discoloration of body secretions?
rifampin
41
What TB medication may cause visual issues?
ethambutol
42
Drugs ending in -thromycin, such as azithromycin are within what class?
macrolides
43
A 25 year old female is prescribed isotretinoin for acne, what is a critical patient education point that the nurse should make?
avoid pregnancy, as this will cause birth defects. Monthly pregnancy tests. 2 tests before being prescribed.
44
What is tamoxifen used in the treatment of?
breast cancer
45
What are adverse effects of tamoxifen?
Endometrial cancer/vaginal bleeding, thromboembolisms/blood clots, menopause symptoms(hot flash, decreased libido, vaginal dryness), hypercalcemia, N/V
46
What medication stops growth of breast cancer cells by blocking estrogen?
Tamoxifen
47
What are the indications for hydroxyurea?
leukemia, ovarian, sickle cell anemia, and squamous cell cancer
48
What are the indications for nitrofurantoin?
urinary tract infection (UTI) & cystitis (bladder infection)
49
Bactericidal are drugs that:
Kill bacteria
50
How do bacteriostatic drugs work?
inhibit bacterial growth
51
What causes drug resistance? What can this lead to?
Overuse and not taking full course of prescribed medications. It makes the infection difficult to treat.
52
This is a type of secondary infection that occurs following the disturbance of the body's normal flora, such as after raking broad spectrum antibiotics.
superinfection
53
What is culture? What is sensitivity?
defines the type of bacteria. Describes what drugs can treat it
54
What should those with an allergy to penicillin wear?
medical allergy alert bracelet
55
What should be assessed before giving cefazolin?
allergy to penicillin
56
Fatal colitis is the black box warning for what medication?
Clindamycin
57
If a patient were to develop Steven Johnson's syndrome while taking TMP-SMZ (trimethoprim sulfamethoxazole, a sulfonamide), what may their initial symptoms be?
flu-like symptoms (fever, malaise, fatigue, coughing)
58
What patient teaching should be given for a patient on a macrolide, such as fidaxomicin?
report diarrhea/hearing changes/superinfection (white-cheesy discharge), take probiotic to prevent C. diff., finish full regimen, 2hr before/after antacids, avoid sun, barrier method for birth control
59
what is pseudomembranous colitis?
c. diff
60
Because of their robust nature, what must be received prior to giving clindamycin/lincomycin?
sensitivity (it is only given when we know that it is necessary for the specific bacteria)
61
What are the adverse effects of lincosamides (clindamycin)?
c.diff (diarrhea), rash, fatal colitis
62
what type of drugs end in -floxacin/-xacin (ex. ciprofloxacin)?
fluoroquinolones
63
What are the nursing considerations for ciprofloxacin?
teach Pt to: avoid sun, avoid caffeine, avoid strenuous exercise (excess pressure on tendon) ;report superinfection signs, tendon/muscle pain. monitor kidney function. 2L fluid/day
64
What are the indications for metronidazole?
vaginal trichomoniasis, giardiasis (diarrheal disease), H. pylori, and C. diff
65
What is a common effect of metronidazole?
dark/red-brown urine
66
Because of its risk for a disulfiram like reaction (facial flushing, nausea, vomiting, sweating), patients taking metronidazole should avoid:
alcohol
67
what action should be taken following the administration of liquid nitrofurantoin due to the risk of teeth staining?
rinse mouth
68
What must female patients who are of child-bearing age sign prior to being prescribed isotretinoin?
I-pledge (a statement of agreement to get pregnancy tests before and during medication, as well as to using 2 forms of contraception)
69
What may be the emotional effect of isotretinoin?
depression/suicidal thoughts
70
Why should individuals taking sulfamethoxazole increase their fluid intake?
prevent crystalluria
71
What medication may cause patients to experience a metallic taste and discolored urine?
metronidazole
72
Metallic taste, brown urine, Steven-Johnson, disulfiram-like reaction, and neuro/CNS toxicity are possible effects of which drug?
metronidazole
73
This drug can be used in the treatment of vaginal trichomoniasis, giardiasis, helicobacter pylori and C.diff:
metronidazole
74
What drug may be used in the treatment of the following: UTI, pneumocystis carinii pneumonitis/Jiroveci pneumoniae?
TMP-SMZ (trimethoprim-sulfamethoxazole)
75
What is the recommended infusion for ciprofloxacin?
60 minimum, but 60-90mins
76
Arthropathy and achilles tendon rupture may occur with which medication?
ciprofloxacin
77
Why should individuals taking ciprofloxacin avoid strenuous activity?
to put let pressure on the legs due to the possibility of achilles tendon rupture
78
Fatal colitis is adverse effect of which antibacterial medication?
clindamycin
79
What medication may be utilized in the treatment of bacterial pneumonia, legionnaires disease, chlamydia, and pertussis?
azithromycin
80
What can taking a daily probiotic prevent for those taking antibiotics?
pseudomembranous colitis
81
What medication may be used to treat Lyme disease?
doxycycline
82
Why should doxycycline not be given to children who are younger than 8 yrs old?
teeth staining
83
What is a rarely used route for doxycycline?
intramuscular
84
What should be taken throughout the course of gentamicin administration?
peak and trough
85
Red man syndrome may occur as effect of infusing which medication too quickly?
vancomycin
86
What can vancomycin be used to treat?
C.diff, MRSA, bacterial bone/skin infections
87
Which tuberculosis medication from RIPE may cause gout? Why?
ethambutol because it may increase uric acid levels
88
What are symptoms of liver damage?
abdominal pain/swelling, N/V, jaundice, severe fatigue
89
What is amphotericin B?
a highly toxic anti-fungal medication only used in the treatment of life-threatening fungal infections
90