Exam 5 part 3 Flashcards
(35 cards)
What drug used for thyroid replacement interacts with warfarin by increasing its effect? What should be monitored closely?
levothyroxine
PT/INR and bleeding
What drug interactions occur with levothyroxine?
warfarin and digoxin
Because vitamins and supplements can decrease the absorption of levothyroxine, when should they be taken?
4 hrs after taking levothyroxine
Levothyroxine decreases the effect of digoxin, so which symptoms should be monitored very closely?
s/s heart failure (edema, SOB< crackles, activity intolerance, etc)
What s/s may indicate overmedication of levothyroxine?
hyperthyroidism (tachycardia, weightloss, hyperactivity)
What adverse effects may occur in a patient with a thyroid replacement patient receiving levothyroxine?
aFIB, bone loss, overmedication/hyperthyroidism
What are the indications of methimazole and propylthiouracil?
hyperthyroidism, goiter, thyroid storm, and Grave’s disease
If crushing a levothyroxine tablet, what should it be mixed with?
water
If a patient is receiving propylthiouracil for hyperthyroidism, what tests are important to monitor frequently?
liver function tests (Black box warning for hepatic toxicity)
What is a major adverse effect concern with antithyroid medications (methimazole)?
hypothyroidism
what pregnancy category is methimazole (drug for hyperthyroidism)?
Category D
what food group should those taking methimazole avoid?
sea food due to iodine content
Agranulocytosis may occur as a result of receiving methimazole, so this assessment is indicated?
CBC to monitor for agranulocytosis( low wbc) that may lead to infection
What symptoms may occur as a result of stopping methimazole abruptly?
thyroid storm/crisis (tachycardia, fever, flushing, restlessness, behavior changes)
what medications may be used in diabetes insipidus?
vasopressin and desmopressin
What adverse effect is a black box warning for desmopressin?
severe hyponatremia
What s/s may occur if vasopressin results in overhydration?
sleepiness, difficulty arousing, headache, and mental status changes)
What adverse effects may occur with antidiuretic drugs?
MI, hyponatremia, and over absorption of water
Because of the risk for hypothyroidism-related bradycardia, the nurse should teach the patient taking methimazole (antithyroid drug) to monitor what?
self-monitor pulses
What lab interventions should be implemented for a patient receiving vasopressin or desmopressin?
urine specific gravity and osmolality, I & O, BUN/creatinine, sodium and potassium
what are the indications for calcitonin-salmon?
hypercalcemia, Paget’s disease, osteoporosis in post-menopausal women
What adverse effects should be monitored in those receiving calcitonin salmon?
hypocalcemia (muscle spasms, seizures, paresthesia)
what are side effects that may occur with calcitonin-salmon?
GI disturbances, skin rash, nasal irritation, flushing
If a patient taking taking risedronate (bisphosphonates) develops musculoskeletal pain, what can the nurse teach them to take?
acetaminophen