Exam 3 - Bone and Joint Infection

Question 1

types of bone and joint infections

Answer 1

osteomyelitis
septic arthritis
prosthetic joint infections

Question 2

do we need samples and cultures in bone and joint infections?

Answer 2

yes

Question 3

what is the most common organism with bone and joint

Answer 3

staph aureus

Question 4

what is the duration and intensity for bone and joint infections

Answer 4

therapy typically given longer and higher doses (weeks to months)

Question 5

why is abx therapy in bone and joint infections difficult for patient?

Answer 5

adverse effects
insurance and cost
patient adherence

Question 6

patients who are post surgical should be covered for what additional bacteria?

Answer 6

pseudomonas

Question 7

presentation of osteomyelitis

Answer 7

pain, swelling in area of infection
fever
can be acute or chronic

Question 8

diagnosis of osteomyelitis

Answer 8

elevated WBC, ESR, CRP
XRay, CT or MRI
bone aspiration, biopsy, surgery
pathology

Question 9

what are the two main approaches for osteomyelitis treatment

Answer 9

antibiotics & surgery

Question 10

can you hold antibiotics in osteomyelitis

Answer 10

yes while awaiting biopsy/surgery if the patient is stable

Question 11

empiric therapy for osteomyelitis

Answer 11

Pick one of: cefazolin, ceftriaxone, cefepime, pip/tazo, amp/sul, meropenem, cipro, levo
AND
Pick one: vanc, dapto, or linezolid

Question 12

how long should osteomyelitis be treated

Answer 12

4-8 weeks typically

Question 13

what are the oral options for osteomyelitis

Answer 13

strep - amox, cephalexin, clindamycin
MSSA - cephalexin, cefadroxil, TMP/SMX, linezolid
MRSA - linezolid, TMP/SMX, clindamycin
GNRs - TMP/SMX, fqs

Question 14

what is a novel approach option for osteomyelitis

Answer 14

dalbavancin

Question 15

empiric therapy for septic arthritis

Answer 15

same as osteomyelitis

Question 16

empiric therapy for prosthetic joint infection

Answer 16

same as osteomyelitits