Exam 3 Drug Facts(Misc. Lectures) Flashcards
(107 cards)
Mechanism of Bisphosphonates
Becomes part of the bone permanently, making bone resistant to resorption
Osteoblasts
involved in the buildup of bone
bone forming cell
decreased activity in older age
Osteoclasts
involved in bone resorption-removal of calcium of bone into the blood
Always active
Generic of Fosamax
alendronate
Dosage form of Fosamax
tablet
Dosage form of alendronate
tablet
strengths of Fosamax
35mg
70mg
strengths of alendronate
35mg
70mg
Dosing interval of Fosamax
1 weekly
Dosing interval of alendronate
1 weekly
How should you take bisphosphonates
Take on empty stomach
Take with water
Remain upright for 30 minutes
Generic of Fosamax Plus D
alendronate + cholecalciferol
Synonyms for calcium
cholecalciferol
ergocalciferol
Dosing interval of Fosamax Plus D
1 weekly
Dosage form of Fosamax Plus D
tablet
comes in a package of 4
Strengths of Fosamax Plus D
70mg alendronate + 70mcg cholecalciferol
70mg alendronate + 140mcg cholecalciferol
What does 70 mcg of cholecalciferol equal?
2800 IU Vit. D
What does 140mcg of cholecalciferol equal?
5600 IU Vit.D
Dosage form of Rx Vit. D supplement
capsule
Strength of Rx Vit. D supplemet
50,000 IU
Dosing interval for Rx Vit. D
1 weekly
Indication for Rx Vit. D supplemengt
used to treat Vit. D deficiency
How much Vit. D is needed to prevent deficiency?
400 IU
available OTC
Why is Vit. D needed?
Needed to promote absprotion of calcium
Vit. D deficiency leads to increased osteoclast activity =osteopororsis