Exam Guru 2 Flashcards

1
Q

Agranulocytosis / neutropenia

- other findings?

A

Carbamazepine
Clozapine

Bronchitis / pneumonia
Sinusitis / maxillary tenderness
Postural HA

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2
Q

Carbamazepine can cause agranulocytosis.

- other serious SE’s?

A

Stevens-Johnson
Teratogenic

Overdose: hepatotoxic, sedation

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3
Q

If Valproate must be used in pregger, what also give?

A

Folate, due to neural tube defects

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4
Q

Examples of social phobia?

A

Public speaking, urinating,

aka social anxiety disorder

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5
Q

Pseudohallucination vs. illusion

A

Pseudo - brain fills in what it thinks it should have seen

Illusion - brain misinterprets a genuine sensory perception

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6
Q

When use supportive psychotherapy?

A

High-fn pt in acute crisis (adjustment disorder)

Low-fn pt w/ schizo/MDD with psychosis

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7
Q

What illicit drug can trigger decompensation in schizophrenia patients?

A

Cannabis

  • in adolescence increases risk developing schizo
  • accelerates progression to schizo in pt’s who would have gotten it at a later age
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8
Q

What drugs can produce psychosis indistinguishable from schizophrenia?

A

PCP and ketamine

- both block NMDA receptors

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9
Q

Synthetic cannabinoids can cause…

A

Frank psychosis in pt’s w/ no risk factors

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10
Q

Anorexia nervosa can often co-present with MDD

Treat with what?

A

Citalopram or other SSRI

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11
Q

Why did TCA’s fall out of favor?

A

QT prolongation - get semi-annual EKG
Delirium in pt’s w/ dementia
Anti-cholinergic effects
Orthostatic hypotension

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12
Q

One change in kids regarding depression?

A

Instead of a low mood may be irritable

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13
Q

What rule out in ED before dx of schizophrenia/schizophreniform disorder can be made?

A

Substance-induced psychosis

- do a urine tox screen

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14
Q

TCA’s are not recommended in the elderly.

- why get increased head injuries and hip fractures?

A

Falls - due to orthostatic hypotension

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15
Q

Motor immobility + mutism
Normal vital signs
Background of what?

A

Catatonia

- background of schizophrenia

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16
Q

What make you think postpartum psychosis instead of depression?

A

Auditory hallucinations and/or delusions

  • reinforce unfounded idea that pt will be a bad mom
  • baby’s life will not be worth living
17
Q

Why abrupt alcohol withdrawal deadly?

A

Down regulation of GABA receptors

  • alcohol enhances GABA so get down regulation of GABA receptors
  • then when alcohol is removed don’t have CNS inhibitory NT
  • get CNS excitation…tremor, agitation, SEIZURE
18
Q

What kills pt’s in delirium tremens?

A
#1 Autonomic instability
Also get seizures, delirium, severe tremors
19
Q

How treat personality disorders? Why?

A

Psychotherapy

  • they are egosyntonic - pt’s believe their trait is perfectly acceptable despite functional problems
  • tend to be more psych then biological
20
Q

Cognitive triad of depression:

A

1 - negative views of oneself
2 - negative views of the world
3 - negative views of the future

21
Q

Mescaline

A

Hallucinogen found in peyote

  • visual sensations/hallucinations
  • increased Serotonin neurotransmission
  • have clear memories of what you saw
22
Q

Rapid cycling bipolar disorder

A

4+ mood episodes in one year

23
Q

What area of brain responsible for schizo’s hearing voices?

A

Temporal lobe

24
Q

Cocaine-induced depression

A

Treat w/ inpatient or intensive outpatient drug rehabilitation program

(don’t think of this as isolated depression; it will likely resolve in a few weeks without meds)

25
Q

Criteria for manic?

A

3+ symptoms for 1+ week period

DIG FAST distract/impulsive/grand/flight
activity/sleep/talkative

26
Q

Sexual abuse w/out treatment can lead to?

A

Borderline personality disorder

PTSD and borderline are commonly comorbid

27
Q

Huntington is choreathoid + volume loss in the ???

A

Caudate Nucleus

28
Q

Parkinson’s is tremor + volume loss in???

A

Substantia nigra