Exam Guru Flashcards

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1
Q

Distinguish PMDD from PMS?

- treat PMDD?

A

Severity - major impairment dysfunction in occupational or social arenas.

SSRI - serotonin hypothesis (5-HT adversely affected by ovarian steroid levels)

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2
Q

Nicotine withdrawal:

A

HA, difficulty concentrating
Constipation
Irritable
Fatigue

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3
Q

What increased in GAD?

A

Cortisol - stress hormone

Increased GC levels produces/exacerbates anxiety and depression

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4
Q

Caffeine intoxication:

A
Psychomotor agitation, restlessness
Nervousness, excitement
Rambling flow of thought and speech
Diuresis, GI disturbance
Tachycardia
Flushed face
Muscle twitching
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5
Q

Why orthostatic hypotension with risperidone?

A

alpha-1 antagonist
- impaires NE binding to alpha 1

Risperidone/palperidone
Clozapine / thioridazine

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6
Q
Schizotypal personality disorder
vs. 
Delusional disorder
vs. 
Paranoid personality disorder
A

Schizotypal: magical thinking, social isolation

Delusional disorder: 1+ month delusions with NO significant impairment…single fixed delusion

Paranoid personality: >1 delusion

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7
Q

ECT primarily helps with…

A

Mood disorders
Psychotic disorders

(NOT anxiety or OCD)

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8
Q

Hx unrelated symptoms in different organ systems

No clear pathology on physical examination

A

Somatic symptom disorder
- underlying psychosocial stressor

Females before age 30!!
Around time of first pregnancy!!!

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9
Q

Single pseudo-neurological symptom in response to psychological stress…

A

Conversion disorder

the symptom is often severe

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10
Q

How treat somatic symptom disorder?

A

Regular monthly follow-up visits with same primary care physician for education

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11
Q

Buprenorphine

A

Partial opiate agonist

  • poor binding so hard to OD
  • also blocks other opiates from binding

Slow onset of action like Methadone

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12
Q

Psilocybin

A

Psychedelic compound - mushrooms

  • visual hallucinations (aware not real)
  • no respiratory depression
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13
Q

Which has higher teratogenatic effects, lithium or carbamazepine?

A

Carbamazepine - neural tube defects
Lithium less but Epstein’s anomaly - 1st trip = atrialization of right ventricle.

Haldol good in pregger

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14
Q

Bupropion good for depression and also…

A

Desire to quit smoking

Lack of sexual side effects

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15
Q

Lack of erection, neurotransmitter?

A

Point & Shoot

  • Point = Parasympathetic = erection = ACh
    • so Anti-cholinergic activity can cause erection problems
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16
Q

Fear of having panic attack in public place - difficult to escape?

A

Agoraphobia

17
Q

1+ month recurrent panic attacks, worry about future attacks, change of behavior to avoid attacks.

A

Panic disorder

18
Q

Treat panic disorder?

A

SSRI, BDZ, psychotherapy

19
Q

Avoidant personality disorder?

A

Desire relationships
Fear rejection
Social anxiety

20
Q

Adverse effect of bupropion?

A

Lower seizure threshold

21
Q

Dilated pupils
Can see sounds
Tremor
What drug? How reverse?

A

LSD - serotonin hallucinations

Give 5-HT blocker like ziprasidone (2nd gen AS)

22
Q

Which two BDZ’s give for DT’s in pt w/ bad liver?

A

Lorazepam & Oxazepam

- metabolized by glucuronidation

23
Q
Low body weight
Intense fear of gaining weight
Amenorrhea in females
Hypotension
Bradycardia
A

Anorexia nervosa

  • can’t use bupropion due to lowering seizure threshold
  • can’t use in weight disorders - tonic-clonic seizures
24
Q

What med lowers BP and decreases incidence of nightmares in pt’s w/ PTSD?

A

Prazosin (and terazosin)

  • alpha blocker, so lowers BP
  • decreases nightmares
25
Q

How treat PTSD?

A

SSRI + cognitive behavioral therapy

26
Q

Bulimia nervosa develop what acid-base abnormality?

A

Non-anion gap
Metabolic alkalosis
- with respiratory compensation

27
Q

What 2 things do you always see in bulimia nervosa?

A

Binge eating

Normal or increased BMI

28
Q

Drug used for GAD that has little to no sexual side effects?

A

Mirtazapine: alpha 2 antagonist

  • atypical antidepressant
  • appetite stimulation
  • sedation
29
Q

Describe GAD?

A

Excessive anxiety and worry in everyday life situations
Insomnia + unsatisfying sleep
May have panic attacks
Muscle tension, irritability