Exam III-Basal Ganglia Flashcards Preview

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Flashcards in Exam III-Basal Ganglia Deck (15):
1

Caudate + Globus Palladus + Putamen =

Corpus Striatum

2

Putamen + Globus Palladus =

Lenticular Nucleus

3

Caudate + Putamen =

Striatum or NeoStriatum

4

What are the three main functions of the basal ganglia that Dr. L kept saying?

Motor Movement, Emotional, and Cognitive

5

Do Lesions of the Basal Ganglia lead to Paralysis?

HELL NAW

6

What is the direct pathway with + and -?

Cortex + -->Caudate & Putamen - --> Globus PalladusInterna/Substantia NigraReticular - -->Thalamus + -->Cortex (other sources then stimulate the Thalamus with then stimulates the cortex)

7

What is the indirect pathway with + and -?

Cortex + --> Caudate & Putamen - --> Globus PalladusExterna - --> SubThalamic Nucleus + -->Globus PalladusInterna/Substantia NigraReticulum - --> Thalamus

8

What two things does dopamine do to in the SN circuit?

It excites the direct pathway and Inhibits the indirect pathway

9

Where does dopamine come from SN Pars Compacta or SN pars Retciulara

SN Compacta

10

Which BG disorder will arise from a unilateral lesion to the sub thalamic nucleus?

HemiBallisms

11

Is movement affected in lesions of the Caudate nucleus?

Nope, just complex behaviors and cognitive functions

12

What are the four cardinal features of Parkinson's Disease?

Tremor, Rigidity, BradyKinesia, Postural instability

13

What, concerning the pathways is a cause for Huntington's Disease?

Loss of the Indirect pathway.

14

What is the main manifestation of Huntington's Disease?

Chorea

15

What is the cause of the over stimulation of the cortex in ballism?

Loss of the sub thalamic nucleus causes loss of the indirect pathway