Flashcards in Exam III-Basal Ganglia Deck (15):
Caudate + Globus Palladus + Putamen =
Putamen + Globus Palladus =
Caudate + Putamen =
Striatum or NeoStriatum
What are the three main functions of the basal ganglia that Dr. L kept saying?
Motor Movement, Emotional, and Cognitive
Do Lesions of the Basal Ganglia lead to Paralysis?
What is the direct pathway with + and -?
Cortex + -->Caudate & Putamen - --> Globus PalladusInterna/Substantia NigraReticular - -->Thalamus + -->Cortex (other sources then stimulate the Thalamus with then stimulates the cortex)
What is the indirect pathway with + and -?
Cortex + --> Caudate & Putamen - --> Globus PalladusExterna - --> SubThalamic Nucleus + -->Globus PalladusInterna/Substantia NigraReticulum - --> Thalamus
What two things does dopamine do to in the SN circuit?
It excites the direct pathway and Inhibits the indirect pathway
Where does dopamine come from SN Pars Compacta or SN pars Retciulara
Which BG disorder will arise from a unilateral lesion to the sub thalamic nucleus?
Is movement affected in lesions of the Caudate nucleus?
Nope, just complex behaviors and cognitive functions
What are the four cardinal features of Parkinson's Disease?
Tremor, Rigidity, BradyKinesia, Postural instability
What, concerning the pathways is a cause for Huntington's Disease?
Loss of the Indirect pathway.
What is the main manifestation of Huntington's Disease?