Flashcards in Exam IV Non-nitrogen Protein, Kidney & Liver functions, Enzymes, Cardiac markers Deck (98)
What is the substrate for the enzyme aspartate amino transferase (AST)?
alpha ketoglutamic acid
Creatinine is formed from the breakdown of?
PSP is removed from the blood by the?
What is the principle of the Berthelot reaction and what substances can cause falsely elevated values in the reaction?
hydrolysis of urea into ammonium carbonate by the enzyme urease; cause blue colored compound
high levels of ammonia or bilirubin
Increased ALT values are associated with disease of?
What is the normal value for serum AST at 37?
Which anticoagulant should NOT be used for the urease testing?
What is the normal percentage for the CK-MB isoenzyme?
less than 6%
What reagent is used in the measurement of uric acid?
Creatinine clearance is used to assess the rate of?
(Ucr * Vu)/(Pcr * t)
What additional info must be know to calculate Crcl if the patient is an infant, young child or adolescent?
body surface area
What is the most common endogenous substance used to assess GFR?
Serum creatine kinase is most often used in diseases of?
Serum lipase levels are elevated in disease of?
Diacetyl monoxime reacts with ? to produce a yellow product?
What is uremia?
abnormal substances of urea in the blood
What is the normal value for CK in males at 37?
Three ways that can be used in the lab to measure the rate of an enzymatic reaction.
Multiple point assay
Kinetic point assay
Define the International Unit (IU)
quantity of enzyme that will catalyze one micromole (umol) of substrate per minute
What is the peak absorbance of reduced NAD (NADH)?
The Jaffe reaction is used to measure?
Which non-protein nitrogen component comprises the largest fraction of NPN in the blood?
Which enzyme is useful in the detection of insecticide poisoning?
Low levels ow wchich enzyme can cause a patient to be susceptible to prolonges apnea when exposed to certain types of anesthesia?
Increased levels of LD-a and LD-5 are associated with?
acute hepatic disease
Gout is caused by the deposition of ? in joints and other tissues.
What is the cilnical significance of a mildly elevated ALP in a teenager?
No significance: still growing
What is the normal ration of BUN to creatinine?
10:1 to 15:1