Extracellular matrix Flashcards
T/F Laminins and fibronectins are found in soluble and insoluble forms.
True
What are tight junctions networks composed of
Thin fibrils where proteins remain embedded.
What is the major structural protein of the Extracellular matrix of animals
Collagen
What is the localization of GAP junctions
They project out from the plasma membrane of 2 neighboring cells.
T/F Mutations in laminins and fibronectins cause epidermolysis bullosa
False
What causes epidermolysis bullosa
Mutations in laminins and collagen
Despite the fact that they possess no intrinsic signaling ability, integrins are still considered signaling receptors. Why?
Development is in response too signals.
Bind to signaling proteins.
Tissue cells are connected to the extracellular matrixby receptors that bind to the adhesive protein ___?
Collagen
Where are both Laminins and fibronectins found?
In the extracellular matrix
What do both laminins and fibronectins bind to?
Collagen and integrins
What is the domain like of only Collagen, not laminin or fibronectin?
Collagen has a triple helical domain
What are GAP junctions?
Protein structures that directly transfer small molecules between two cells.
What are the three repeating amino acids that commonly exist in coiled collagen proteins.
Proline, hydroxyproline, and Glycine.
Where are laminins primarily found?
In the Basal Lamina
What connects cells in plants to equalize the ionic concentrations of their cytosol
Plasmodasta
