FA synthesis

Question 1

FA synthesis begins with

Answer 1

Acetyl coA

Question 2

The product of fatty acid synthesis sis

Answer 2

Palmitic acid (16 carbon fatty acid)

Question 3

3 stages occur in the cytosol of liver/fat cells

Answer 3

1. Acetyl coA is transported from the mitochondria into the cytosol. (must be converted to citrate first then back to acetyl coA)
2. Acetyl coA is activated to produce malonyl coA
3. Five step elongation cycle that produces palmitic acid (requires NADPH- source of electrons in anabolic reactions)

Question 4

How can palmitic acid be modified in the smooth ER?

Answer 4

-# of carbons can be
-changed
double bonds can be introduced
-Alcohol and other groups added

Question 5

Where does fatty acid synthesis occur

Answer 5

Cytosol